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    Article

    Overexpression of PTP1B in human colorectal cancer and its association with tumor progression and prognosis

    Protein tyrosine phosphatase 1B (PTP1B) is a non-transmembrane protein tyrosine phosphatase that has been implicated in cancer pathogenesis. However, the expression level and the role of PTP1B in the developme...

    Queting Chen, Yong Li, Zhong Li, Qun Zhao, Liqiao Fan in Journal of Molecular Histology (2014)

  2. Article

    Open Access

    RNF180 mediates STAT3 activity by regulating the expression of RhoC via the proteasomal pathway in gastric cancer cells

    Ring finger protein 180 (RNF180) is an important member of the E3 ubiquitin ligase family. As a tumor suppressor gene, RNF180 is significantly associated with the prognosis of patients with gastric cancer (GC)...

    Zizhen Wu, Huifang Liu, Weilin Sun, Yingxin Du, Wenting He in Cell Death & Disease (2020)

  3. Article

    Open Access

    DNMT3A-mediated silence in ADAMTS9 expression is restored by RNF180 to inhibit viability and motility in gastric cancer cells

    ADAMTS9 belongs to the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family, and its expression is frequently silenced due to promoter hypermethylation in various human cancer...

    Weilin Sun, Gang Ma, Li Zhang, Pengliang Wang, Nannan Zhang in Cell Death & Disease (2021)