109 Result(s)
-
Article
Three isoforms of annexin I are preferentially expressed in normal esophageal epithelia but down-regulated in esophageal squamous cell carcinomas
The development and progression of human cancer are believed to be due to the alterations of multiple genes or/and their protein products. For identifying the proteins associated with esophageal cancer, we ana...
-
Article
Study on Treatment of polycystic ovarian syndrome with Infertility by combined therapy of Chinese herbal medicine and compound cyproterone acetate
Objective: To evaluate the effect of combined therapy of Chinese herbal medicine and compound cyproterone acetate (CPA) in treating non-obesity polycystic ovarian syndrome (PCOS) and to explore i...
-
Article
Disruption of the Rad9/Rad1/Hus1 (9–1–1) complex leads to checkpoint signaling and replication defects
The checkpoint sliding-clamp complex, Rad9/Rad1/Hus1, plays a critical role during initiation of checkpoint signals in response to DNA damage and replication disruption. We investigated the impact of loss of R...
-
Article
ERβ exerts multiple stimulative effects on human breast carcinoma cells
Recent studies of ERs in breast cancer have demonstrated the existence of ERβ in addition to ERα. Some clinical data indicated that ERβ had prognostic value for patient's survival, which suggested that ERβ plays ...
-
Article
Effects of Systemic Administration of Iptakalim on Extracellular Neurotransmitter Levels in the Striatum of Unilateral 6-Hydroxydopamine-Lesioned Rats
The function of ATP-sensitive potassium (KATP) channels in nigrostriatal pathway in Parkinson's disease (PD) was studied by employing a novel KATP channel opener iptakalim (Ipt). Apomorphine-induced rotation b...
-
Article
Limitation of the Augmentation Index for Evaluating Arterial Stiffness
Although the augmentation index (AIx) is widely used to evaluate arterial stiffness in clinics and research, some conflicting data exist in regard to its validity. We therefore performed a series of studies to...
-
Article
Proteomics in discovery of hepatocellular carcinoma biomarkers
To discover new proteomic biomarkers of hepatocellular carcinoma.
-
Article
Effects of various factors on proliferation capacity and cytotoxicity of induced CIK of patients with tumor in vitro
To evaluate effects of different factors on proliferation capacity and cytotoxicity of induced cytokine induced killer (CIK) cells in vitro, so as to provide experimental basis for cell therapy of CIK in tumor.
-
Article
The Study of Aortic Stiffness in Different Hypertension Subtypes in Dialysis Patients
The aim of this study was to validate whether differences in aortic stiffness are responsible for the differences in cardiovascular mortality among hypertension subtypes. Twenty hundred and fifty continuous am...
-
Article
Interon-gamma enhances the antitumor effect of all-trans retinoic acid on hepatocellular carcinoma cells by inhibiting the expression of nuclear factor-kappaB
To explore the combination effects of all-trans retinoic acid (ATRA) with interferon-gamma (IFN-γ) on human hepatocarcinoma cell line SMMC-7721 and the mechanism of action.
-
Article
Effect of Jianpi Huoxue decoction (健脾活血方)-containing serum on tumor necrosis factor-α secretion and gene Expression of endotoxin receptors in RAW264.7 cells induced by lipopolysaccharide
To evaluate the effect of Jianpi Huoxue decoction (健脾活血方, JHD)-containing serum on tumor necrosis factor-α (TNF-α) secretion and endotoxin receptor gene expression in RAW264.7 cells induced by lipopolysacchari...
-
Article
Trans-upper-sternal Approach to the Cervicothoracic Junction
From August 1999 to February 2006, 11 patients with cervicothoracic lesions (eight males, three females; age range, 17–77 years) were surgically treated using the trans-upper-sternal approach. Combined cervico...
-
Article
Open AccessIncidence of chemotherapy-induced amenorrhea associated with epirubicin, docetaxel and navelbine in younger breast cancer patients
The rates of chemotherapy-induced amenorrhea (CIA) associated with docetaxel-based regimens reported by previous studies are discordant. For navelbine-based chemotherapies, rates of CIA have seldom been reported.
-
Article
Research progress on the mechanism of single-Chinese medicinal herbs in treating diabetes mellitus
Treating diabetes mellitus (DM) with Chinese medicine (CM) has had a few thousands years of history. Past Chinese medical texts had already recorded numerous medicinal herbs as well as recipes for treating DM ...
-
Article
Incidence and mortality trend of cervical cancer in 11 cancer registries of China
In many countries, the cervical cancer prevalence has declined but less information about the changes is available in China. This study aims to understand the epidemiological characteristics and trend of cervi...
-
Article
Open AccessATP synthase ecto-α-subunit: a novel therapeutic target for breast cancer
Treatment failure for breast cancer is frequently due to lymph node metastasis and invasion to neighboring organs. The aim of the present study was to investigate invasion- and metastasis-related genes in brea...
-
Article
Scanning electron microscopy study of cavity preparation in deciduous teeth using the Er:YAG laser with different powers
Using scanning electron microscopy (SEM) we evaluated the morphology of cavity surfaces in deciduous teeth prepared in vitro with the Er:YAG laser with different power parameters. Eight extracted cavity-free d...
-
Article
XPC polymorphism increases risk of digestive system cancers: Current evidence from a meta-analysis
Xeroderma pigmentosum complementation group C (XPC) participates in the initial recognition of DNA damage during nucleotide excision repair process in global genomic repair. Our meta-analysis was performed to ...
-
Article
HER2-specific T lymphocytes kill both trastuzumab-resistant and trastuzumab-sensitive breast cell lines in vitro
Although the development of trastuzumab has improved the outlook for women with human epidermal growth factor receptor 2 (HER2)-positive breast cancer, the resistance to anti-HER2 therapy is a growing clinical...
-
Article
Open AccessVisceral larva migrans associated with earthworm and gecko ingestion: a case report
Visceral larva migrans is a syndrome caused by an infection with larval helminths, which may result in partial or general pathological changes in host tissues. Due to the difficulty in finding the causative pa...