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  1. No Access

    Article

    A method for isolating and culturing vascular smooth muscle cells from porcine cerebral arteries

    Cerebral blood vessels have unique properties when compared to most peripheral vascular beds. One such property is that large cerebral vessels are involved in the regulation of cerebral vascular resistance. St...

    Hong Tao, Li-Ming Zhang, Manuel R. Castresana, Walter H. Newman in Methods in Cell Science (1996)

  2. Article

    Enzymatic activity characterization of SARS coronavirus 3C-like protease by fluorescence resonance energy transfer technique

    To characterize enzymatic activity of severe acute respiratory syndrome (SARS) coronavirus (CoV) 3C-like protease (3CLpro) and its four site-directed mutants.

    Shuai Chen, Li-li Chen, Hai-bin Luo, Tao Sun, **g Chen in Acta Pharmacologica Sinica (2005)

  3. Article

    Protective effects of cariporide on endothelial dysfunction induced by high glucose

    To explore the effects of cariporide, a selective sodium-hydrogen antiporter inhibitor, on endothelial dysfunction induced by high glucose.

    Shuang-xi Wang, **ao-ming **ong, Tao Song, Li-ying Liu in Acta Pharmacologica Sinica (2005)

  4. Article

    Effects of specific interleukin-1β-converting enzyme inhibitor on ischemic acute renal failure in murine models

    To study the effect of selective interleukin-1 β-converting enzyme (ICE, caspase-1) inhibitor on ischemic acute renal failure (ARF).

    Hua-feng Liu, Dong Liang, Li-ming Wang, Nan Zhou, Cui-wei Yao in Acta Pharmacologica Sinica (2005)

  5. Article

    Antisense oligonucleotides-induced local blockade of T-bet expression leads to airway inflammation in rats

    To explore whether local blockade of T-box expressed in T cells (T-bet) expression in the lungs could lead to airway inflammation.

    Gang Wang, Chun-tao Liu, Zeng-li Wang, Li-li Jiang in Acta Pharmacologica Sinica (2006)

  6. No Access

    Article

    Evaluation of a kinetic uricase method for serum uric acid assay by predicting background absorbance of uricase reaction solution with an integrated method

    A patented kinetic uricase method was evaluated for serum uric acid assay. Initial absorbance of the reaction mixture before uricase action (A 0) was obtained by correcting the absorbance at 293 nm measured befor...

    Fei Liao, Yun-sheng Zhao, Li-na Zhao, Jia Tao in Journal of Zhejiang University SCIENCE B (2006)

  7. Article

    Different effects of nine clausenamide ennatiomers on liver glutathione biosynthesis and glutathione S-transferase activity in mice

    To study the effects of nine synthetic clausenamide with different stereo structures on liver glutathione (GSH) biosynthesis and glutathione S-transferase (GST) activity in mice.

    Yu-qun Wu, Li-de Liu, Hua-ling Wei, Geng-tao Liu in Acta Pharmacologica Sinica (2006)

  8. Article

    Inhibitory effects of cariporide on LPC-induced expression of ICAM-1 and adhesion of monocytes to smooth muscle cells in vitro

    To explore the effects of cariporide on the expression of intercellular adhesion molecule-1 (ICAM-1) and the adhesion of monocytes to vascular smooth muscle cells (SMC) in vitro.

    Zhi Li, Tao Song, Gui-zhen Liu, Li-ying Liu in Acta Pharmacologica Sinica (2006)

  9. No Access

    Article

    Differentiated cells are more efficient than adult stem cells for cloning by somatic cell nuclear transfer

    Since the creation of Dolly via somatic cell nuclear transfer (SCNT)1, more than a dozen species of mammals have been cloned using this technology2. One hypothesis for the limited success of cloning via SCNT (1%–...

    Li-Ying Sung, Shaorong Gao, Hongmei Shen, Hui Yu, Yifang Song in Nature Genetics (2006)

  10. No Access

    Article

    Reply to “On the cloning of animals from terminally differentiated cells”

    **angzhong Yang, Tao Cheng, Li-Ying Sung, Shaorong Gao, Hongmei Shen in Nature Genetics (2007)

  11. No Access

    Article

    Assignment of CCR7 gene to chicken chromosome 27 by radiation hybrid panel map**

    The protein encoded by CC chemokine receptor 7 (CCR7) is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a m...

    Yong Tian, Li-zhi Lu, Yan Fu, Zheng-rong Tao in Journal of Zhejiang University SCIENCE B (2007)

  12. Article

    Nitrofen suppresses cell proliferation and promotes mitochondria-mediated apoptosis in type II pneumocytes

    To characterize the molecular mechanisms of nitrofen-induced pulmonary hypoplasia.

    Qiang-song Tong, Li-duan Zheng, Shao-tao Tang, Guo-song Jiang in Acta Pharmacologica Sinica (2007)

  13. Article

    FG020326-loaded nanoparticle with PEG and PDLLA improved pharmacodynamics of reversing multidrug resistance in vitro and in vivo

    FG020326, a novel imidazole derivative, is a potent multidrug-resistance (MDR) modulator in vitro and in vivo. However, FG020326 is insoluble. PEDLLA-FG020326 is a FG020326-loaded nanoparticle formed with diblock...

    Wen-**g Deng, **ao-qiang Yang, Yong-ju Liang, Li-ming Chen in Acta Pharmacologica Sinica (2007)

  14. No Access

    Article

    Characterizing and estimating rice brown spot disease severity using stepwise regression, principal component regression and partial least-square regression

    Detecting plant health conditions plays a key role in farm pest management and crop protection. In this study, measurement of hyperspectral leaf reflectance in rice crop (Oryzasativa L.) was conducted on groups o...

    Zhan-yu Liu, **g-feng Huang, **g-**g Shi in Journal of Zhejiang University SCIENCE B (2007)

  15. Article

    Recombinant adeno-associated virus-mediated delivery of antisense angiotensin II receptor 1 gene attenuates hypertension development

    The renin-angiotensin system plays a crucial role in the development and establishment of hypertension, and the pharmacological blockade of the system results in a reduction in blood pressure. In the present s...

    Xu-guang Li, Jiang-tao Yan, **-zheng Xu, Jia-ning Wang in Acta Pharmacologica Sinica (2007)

  16. Article

    Natural jasmonates of different structures suppress the growth of human neuroblastoma cell line SH-SY5Y and its mechanisms

    Recent evidence has indicated that members of natural jasmonates, a family of plant stress hormones, exhibit anticancer activity. The current study was undertaken to investigate the effects of jasmonates on the i...

    Qiang-song Tong, Guo-song Jiang, Li-duan Zheng, Shao-tao Tang in Acta Pharmacologica Sinica (2008)

  17. No Access

    Article

    Expression, purification and characterization of a phyA m -phyCs fusion phytase

    The phyA m gene encoding acid phytase and optimized neutral phytase phyCs gene were inserted into expression vector pPIC9K in correct orientation and tr...

    Li-kou Zou, Hong-ning Wang, **n Pan in Journal of Zhejiang University SCIENCE B (2008)

  18. Article

    Effects of docosahexaenoic acid on large-conductance Ca2+-activated K+ channels and voltage-dependent K+ channels in rat coronary artery smooth muscle cells

    To investigate the effects of docosahexaenoic acid (DHA) on large-conductance Ca2+-activated K+(BKCa) channels and voltage-dependent K+ (KV) channels in rat coronary artery smooth muscle cells (CASMCs).

    Li-hong Lai, Ru-xing Wang, Wen-** Jiang, in Acta Pharmacologica Sinica (2009)

  19. Article

    The efficacy and safety of calcitriol and/or Caltrate D in elderly Chinese women with low bone mass

    To observe the efficacy and safety of Rocaltrol (calcitriol) and/or Caltrate D (calicum carbonate plus vitamin D) in elderly Chinese women with osteopenia or osteoporosis.

    Wei-bo **a, Zhong-lan Zhang, Hong-fu Wang, Xun-wu Meng in Acta Pharmacologica Sinica (2009)

  20. No Access

    Article

    Effects of sevoflurane preconditioning and postconditioning on rat myocardial stunning in ischemic reperfusion injury

    Ischemic preconditioning and postconditioning distinctly attenuate ventricular arrhythmia after ischemia without affecting the severity of myocardial stunning. Therefore, we report the effects of sevoflurane p...

    An-lu Dai, Li-hua Fan, Feng-jiang Zhang in Journal of Zhejiang University SCIENCE B (2010)

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