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Article
Open AccessThe role of mitochondrial dynamics and mitophagy in skeletal muscle atrophy: from molecular mechanisms to therapeutic insights
Skeletal muscle is the largest metabolic organ of the human body. Maintaining the best quality control and functional integrity of mitochondria is essential for the health of skeletal muscle. However, mitochon...
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Article
Plasma membrane-localized hexose transporter OsSWEET1b, affects sugar metabolism and leaf senescence
OsSWEET1b is a hexose transporter protein, which localized in cell membranes and interacting with itself to form homodimer and knockout of OsSWEET1b resulted in reduced leaves sugar content and accelerating leaf ...
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Article
Open AccessExosomal circ_0026611 contributes to lymphangiogenesis by reducing PROX1 acetylation and ubiquitination in human lymphatic endothelial cells (HLECs)
Esophageal squamous carcinoma (ESCC) is a common malignancy that originates in the digestive tract. Lymph node metastasis (LNM) is a complicated process, and tumor lymphangiogenesis has been reported to be ass...
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Article
OsPPR11 encoding P-type PPR protein that affects group II intron splicing and chloroplast development
OsPPR11 belongs to the P-type PPR protein family and can interact with OsCAF2 to regulate Group II intron splicing and affect chloroplast development in rice.
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Article
Different nitrogen sources change the transcriptome of welan gum-producing strain Sphingomonas sp. ATCC 31555
To reveal effects of different nitrogen sources on the expressions and functions of genes in Sphingomonas sp. ATCC 31555, it was cultivated in medium containing inorganic nitrogen (IN), organic nitrogen (ON), or ...
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Article
Expression and Significance of DLL4-–Notch Signaling Pathway in the Differentiation of Human Umbilical Cord Derived Mesenchymal Stem Cells into Cardiomyocytes Induced by 5-Azacytidine
hUCMSCs were isolated and purified from the umbilical cords of normal or cesarean term deliveries under sterile conditions. Flow cytometry analysis revealed that CD13, CD29, CD44, CD90, and CD105 were highly e...
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Article
Establishment of Caenorhabditis elegans SID-1-Dependent DNA Delivery System in Cultured Silkworm Cells
The systemic RNA interference defective-1 (SID-1) can transport double-stranded RNA (dsRNA) into cytosol across the cytoplasmic membrane. We report here that ectopic expression of Caenorhabditis elegans SID-1 all...
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Article
Chloroplast-targeted expression of the codon-optimized truncated cry1Ah gene in transgenic tobacco confers a high level of protection against insects
The study of insect-resistant transgenic tobacco provides a good foundation for the further application of the cry1Ah gene in other important crops. ...
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Article
Acquiring transgenic tobacco plants with insect resistance and glyphosate tolerance by fusion gene transformation
The advantages of gene ‘stacking’ or ‘pyramiding’ are obvious in genetically modified (GM) crops, and several different multi-transgene-stacking methods are available. Using linker peptides for multiple gene t...
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Article
A Causal Analysis of Intra-Abdominal Hemorrhage After Reduced-Size Liver Transplantation in Rat
In this study, we analyzed causes of abdominal hemorrhage after reduced-size liver transplantation in rat. Healthy SD rats (weight range of 260–280 g) underwent liver transplantation, the donors were female an...
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Article
Expressions of three cotton genes encoding the PIP proteins are regulated in root development and in response to stresses
Cotton (Gossypium hirsutum), the most important textile crop worldwide, often encounters water stress such as drought or waterlog during its growth season (Summer). To investigate molecular mechanism of water reg...
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Article
Molecular cloning and characterization of a novel splice variant of the LIM domain family gene, PINCH 2, in human testis
By hybridizing human adult testis cDNA microarrays with human adult and embryo testis cDNA probes, we identified a novel human testis gene, PINCH 2. PINCH 2 expression was 3.4-fold higher in adult than in feta...