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  1. No Access

    Article

    Early effects of hypoxia/reoxygenation on VEGF, Ang-1, Ang-2 and their receptors in the rat myocardium: Implications for myocardial angiogenesis

    Tissue hypoxia has been identified as being a particularly important stimulus for triggering angiogenesis. Here we report early effects of hypoxia/reoxygenation (H/R) on the protein expression profiles and loc...

    Parth S. Ray, Tatiana Estrada-Hernandez… in Molecular and Cellular Biochemistry (2000)

  2. No Access

    Article

    Elements in erythrocytes of population with different thyroid hormone status

    The contents of elements K, Ca, Fe, Cu, Zn, Se, and Rb in erythrocytes of 78 cases with different thyroid hormone status have been measured by proton-induced X-ray emission and neutron activation analysis. Acc...

    Nianqing Liu, **sheng Liu, Qing Xu, Li Zhu… in Biological Trace Element Research (2001)

  3. No Access

    Article

    Study of trace elements in blood of thyroid disorder subjects before and after 131I therapy

    Both trace elements and thyroid hormones play essential roles in the human body. However, the previous results about the interaction between these two factors are often controversially given. In order to make ...

    Fang Zhang, Nianqing Liu, Xuefei Wang, Li Zhu… in Biological Trace Element Research (2004)

  4. No Access

    Article

    Molecular cloning and characterization of a novel splice variant of the LIM domain family gene, PINCH 2, in human testis

    By hybridizing human adult testis cDNA microarrays with human adult and embryo testis cDNA probes, we identified a novel human testis gene, PINCH 2. PINCH 2 expression was 3.4-fold higher in adult than in feta...

    Yun Liu, ** Liu, Jie Chen, Libo Cheng, Qinhong Cao, Li Zhu… in Molecular Biotechnology (2007)

  5. No Access

    Article

    Nerve Growth Factor Protects the Cortical Neurons from Chemical Hypoxia-induced Injury

    Previous studies showed that nerve growth factor (NGF) exerts protective effects on cultured neurons against various kinds of damage. However, a recent publication reported that exposure of NGF-treated PC12 ce...

    Li Zhu, Fang Du, Lei Yang, **ao Mei Wu, Zhong Ming Qian in Neurochemical Research (2008)

  6. No Access

    Article

    Genetic structure and diversity of cultivated soybean (Glycine max (L.) Merr.) landraces in China

    The Chinese genebank contains 23,587 soybean landraces collected from 29 provinces. In this study, a representative collection of 1,863 landraces were assessed for genetic diversity and genetic differentiation...

    Yinghui Li, Rongxia Guan, Zhangxiong Liu, Yansong Ma… in Theoretical and Applied Genetics (2008)

  7. No Access

    Article

    Molecular cloning and sequence analysis of the sisomicin biosynthetic gene cluster from Micromonospora inyoensis

    Micromonospora inyoensis produces sisomicin (Sm), an aminoglycoside antibiotic. The gene cluster of sisomicin biosynthesis spanning ca. 47 kb consists of 37 ORFs encoding various proteins...

    Wun-Rong Hong, Mei Ge, Zhi-Hong Zeng, Li Zhu, Min-Yu Luo, Lei Shao… in Biotechnology Letters (2009)

  8. Article

    Molecular cloning and sequence analysis of the sisomicin biosynthetic gene cluster from Micromonospora inyoensis

    Wen-Rong Hong, Mei Ge, Zhi-Hong Zeng, Li Zhu, Min-Yu Luo, Lei Shao… in Biotechnology Letters (2009)

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  9. No Access

    Article

    Identification and characterization of NARROW AND ROLLED LEAF 1, a novel gene regulating leaf morphology and plant architecture in rice

    Leaf morphology is an important agronomic trait in rice breeding. We isolated three allelic mutants of NARROW AND ROLLED LEAF 1 (nrl1) which showed phenotypes of reduced leaf width and sem...

    Jiang Hu, Li Zhu, Dali Zeng, Zhenyu Gao, Longbiao Guo… in Plant Molecular Biology (2010)

  10. No Access

    Article

    A Synergistic Role of Hyperthermic and Pharmacological Preconditioning to Protect Astrocytes Against Ischemia/Reperfusion Injury

    Recent studies provide solid evidence for the importance to delineate the co-relationship between preconditioning stimuli and therapeutic efficacy of drugs commonly used in clinic. However, very little is know...

    Fang Du, Zhong-ming Qian, Li Zhu, **ao Mei Wu, Wing Ho Yung… in Neurochemical Research (2011)

  11. Article

    Expression of human FUS protein in Drosophila leads to progressive neurodegeneration

    Mutations in the Fused in sarcoma/Translated in liposarcoma gene (FUS/TLS, FUS) have been identified among patients with amyotrophic lateral sclerosis (ALS). FUS protein aggregation is a major pathological hallma...

    Yanbo Chen, Mengxue Yang, Jianwen Deng, ** Chen, Ye Ye, Li Zhu… in Protein & Cell (2011)

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  12. No Access

    Article

    An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity

    The TARDBP gene encodes TDP-43, a multifunctional DNA- and RNA-binding protein involved in many cellular processes. Mutations in TARDBP are associated with TDP-43 proteinopathies. In vivo and in vitro studies of ...

    Weirui Guo, Yanbo Chen, **aohong Zhou, Amar Kar… in Nature Structural & Molecular Biology (2011)

  13. Article

    Dscam mutation leads to hydrocephalus and decreased motor function

    The nervous system is one of the most complicated organ systems in invertebrates and vertebrates. Down syndrome cell adhesion molecule (DSCAM) of the immunoglobulin (Ig) superfamily is expressed widely in the ...

    Yiliang Xu, Haihong Ye, Yan Shen, Qi Xu, Li Zhu, Jianghong Liu… in Protein & Cell (2011)

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  14. No Access

    Article

    Map-based cloning proves qGC-6, a major QTL for gel consistency of japonica/indica cross, responds by Waxy in rice (Oryza sativa L.)

    In this study, one major QTL affecting gel consistency (GC) of japonica/indica cross was identified on chromosome 6 using a DH population. To understand the molecular mechanism that regulates GC in rice grains...

    Yan Su, Yuchun Rao, Shikai Hu, Yaolong Yang, Zhenyu Gao… in Theoretical and Applied Genetics (2011)

  15. No Access

    Article

    Identification and characterization of SHORTENED UPPERMOST INTERNODE 1, a gene negatively regulating uppermost internode elongation in rice

    In rice, the elongated internodes are derived from the vegetative shoot apical meristem (SAM), and the transition of the SAM from the vegetative to the reproductive stage induces internode elongation. In this ...

    Li Zhu, Jiang Hu, Keming Zhu, Yunxia Fang, Zhenyu Gao… in Plant Molecular Biology (2011)

  16. No Access

    Article

    A Causal Analysis of Intra-Abdominal Hemorrhage After Reduced-Size Liver Transplantation in Rat

    In this study, we analyzed causes of abdominal hemorrhage after reduced-size liver transplantation in rat. Healthy SD rats (weight range of 260–280 g) underwent liver transplantation, the donors were female an...

    Liu **g, Li Li, Ran Jiang-Hua, Zhang Sheng-Ning… in Cell Biochemistry and Biophysics (2011)

  17. No Access

    Article

    Type II thioesterase gene (ECO-orf27) from Amycolatopsis orientalis influences production of the polyketide antibiotic, ECO-0501 (LW01)

    ECO-orf27 associated with the cluster of ECO-0501 (LW01) from Amycolatopsis orientalis is deduced to encode a type II thioesterase. Disruption of ECO-orf27 reduced LW01 production by 95 %. Comple...

    Yang Shen, He Huang, Li Zhu, Minyu Luo, Daijie Chen in Biotechnology Letters (2012)

  18. No Access

    Article

    Synthesis and in vitro anticancer activities of novel aryl-naphthalene lignans

    Cancer is one of the leading causes of death in the world. In this study, a series of novel aryl-naphthalene lignans were synthesized and the inhibitory effects of all compounds on cancer cells growth were inv...

    Jie Hui, Yu Zhao, Li Zhu in Medicinal Chemistry Research (2012)

  19. Article

    AMPK interacts with DSCAM and plays an important role in Netrin-1 induced neurite outgrowth

    Down syndrome cell adhesion molecule (DSCAM) acts as a netrin-1 receptor and mediates attractive response of axons to netrin-1 in neural development. However, the signaling mechanisms of netrin-DSCAM remain un...

    Kun Zhu, ** Chen, Jianghong Liu, Haihong Ye, Li Zhu, Jane Y. Wu in Protein & Cell (2013)

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  20. No Access

    Article

    Synthesis and bioevaluation of novel arylnaphthalene lignans as anticancer agents

    Novel arylnaphthalene lignans were synthesized and their structures were established by 1H NMR, 13C NMR, and HRMS. These compounds were evaluated for their in vitro cytotoxicity against cancer cell lines by MTT a...

    Yu Zhao, Jie Hui, Li Zhu in Medicinal Chemistry Research (2013)

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