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Article
Preparation of a purified, inactivated Japanese encephalitis (JE) virus vaccine in Vero cells
An attenuated Japanese encephalitis (JE) virus SA14-14-2 (PDK) was adapted to Vero cells, a continuous cell line that has been licensed for human vaccine production, by serial passages. The resulting virus was...
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Article
Erratum to: Development of a multifunctional and efficient conjugal plasmid for use in Streptomyces spp
Unfortunately, the authors were listed in the wrong order and there were errors in their affiliations. The corrected sequence and the correct affiliations are given below
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Article
Erratum to: An ABC transporter complex containing S-adenosylmethionine (SAM)-induced ATP-binding protein is involved in antibiotics production and SAM signaling in Streptomyces coelicolor M145
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Article
Open AccessCodon optimization, expression, purification, and functional characterization of recombinant human IL-25 in Pichia pastoris
Interleukin (IL)-25 (also known as IL-17E) is a distinct member of the IL-17 cytokine family which induces IL-4, IL-5, and IL-13 expression and promotes pathogenic T helper (Th)-2 cell responses in various org...
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Article
Open AccessInhibiting avian influenza virus shedding using a novel RNAi antiviral vector technology: proof of concept in an avian cell model
Influenza A viruses pose significant health and economic threats to humans and animals. Outbreaks of avian influenza virus (AIV) are a liability to the poultry industry and increase the risk for transmission t...
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Erratum to: Deletion of arcA increased the production of acetyl-CoA-derived chemicals in recombinant Escherichia coli
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Article
Open AccessTransformation of the endochitinase gene Chi67-1 in Clonostachys rosea 67-1 increases its biocontrol activity against Sclerotinia sclerotiorum
Clonostachys rosea is a promising biocontrol fungus active against various plant fungal pathogens. In this study, the endochitinase-encoding gene Chi67-1, the expression of which is sharp...
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Erratum to: The dynamics and mechanism of the antimicrobial activity of tea tree oil against bacteria and fungi
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Article
Open AccessDevelopment of a sandwich enzyme-linked immunosorbent assay for dTMP-GH fusion protein by rational immunogen selection
dTMP-GH is a chimeric protein containing a tandem dimer of thrombopoietin mimetic peptide (dTMP) fused to human growth hormone (hGH) prepared previously by our team. It shows significant bioactivity in promoti...
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Article
Open AccessTranscriptome analysis of a taxol-producing endophytic fungus Cladosporium cladosporioides MD2
The shortage of molecular information for taxol-producing fungi has greatly impeded the understanding of fungal taxol biosynthesis mechanism. In this study, the transcriptome of one taxol-producing endophytic ...
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Article
Open AccessApplication of enhanced electronegative multimodal chromatography as the primary capture step for immunoglobulin G purification
In recent studies, electronegative multimodal chromatography with Eshmuno HCX was demonstrated to be a highly promising recovery step for direct immunoglobulin G (IgG) capture from undiluted cell culture fluid...
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Article
Open AccessMetabolic engineering for the production of isoprene and isopentenol by Escherichia coli
The biotechnological production of isoprene and isopentenol has recently been studied. Isoprene, which is currently made mainly from petroleum, is an important platform chemical for synthesizing pesticides, me...
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Article
Open AccessIsolation and biochemical characterization of a metagenome-derived 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase gene from subtropical marine mangrove wetland sediments
3-Deoxy-d-arabino-heptulosonate-7-phosphate synthase (DAHPS) is a key rate-limiting enzyme in aromatic amino acid anabolism. A new Iβ-type DAHPS gene (aro1A) was identified in a metagenomic library from subtropic...
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Article
Open AccessIdentification and molecular characterization of a psychrophilic GH1 β-glucosidase from the subtropical soil microorganism Exiguobacterium sp. GXG2
The products of bacterial β-glucosidases with favorable cold-adapted properties have industrial applications. A psychrophilic β-glucosidase gene named bglG from subtropical soil microorganism Exiguobacterium sp. ...
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Article
Open AccessInhibitory effects of msFGFR2c on the epithelial-to-mesenchymal transition of AE2 cells in pulmonary fibrosis
In interstitial fibrosis, alveolar epithelial type II (AE2) cells fail to repair damaged epithelium. However, whether this dysfunction is related to fibroblast growth factor (FGF) signal pathway and how it aff...
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Open AccessEvaluating the association between feed efficiency and the fecal microbiota of early-life Duroc pigs using 16S rRNA sequencing
Improving the predication efficiency of porcine production performance at early stage will contribute to reducing the breeding and production costs. The intestinal microbiota had received plenty of attention i...
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Article
Open AccessEffects of Pu-erh and Dian Hong tea polyphenols on the gut-liver axis in mice
Tea polyphenols (TP) are the most biologically active components in tea, with antioxidant, antiobesity, and antitumor properties, as well as the ability to modulate the composition and function of intestinal m...