8 Result(s)
within
Article
Kunming Zhao
-
Article
Open AccessLncRNA ZNF674-AS1 drives cell growth and inhibits cisplatin-induced pyroptosis via up-regulating CA9 in neuroblastoma
Neuroblastoma (NB) is a challenging pediatric extracranial solid tumor characterized by a poor prognosis and resistance to chemotherapy. Identifying targets to enhance chemotherapy sensitivity in NB is of utmo...
-
Article
Impacts of moderateness and cobalancedness in seed mass and coat thickness on seed dispersal effectiveness of Quercus variabilis by rodents
Seed traits are important factors in determining the fitness of seeds under seed dispersal and predation by animals, but the combined effects of conflicting traits (e.g., defense and attraction traits) of seed...
-
Article
iASPP is essential for HIF-1α stabilization to promote angiogenesis and glycolysis via attenuating VHL-mediated protein degradation
Hypoxia-inducible factor-1α (HIF-1α) plays central roles in the hypoxia response. It is highly expressed in multiple cancers, but not always correlated with hypoxia. Mutation of the von Hippel–Lindau (VHL) gen...
-
Article
Open AccessMicrobiome harbored within tumors: a new chance to revisit our understanding of cancer pathogenesis and treatment
-
Article
A novel LncRNA HITT forms a regulatory loop with HIF-1α to modulate angiogenesis and tumor growth
Increasing evidence has indicated that long noncoding RNAs (lncRNAs) play important roles in human diseases, including cancer; however, only a few of them have been experimentally validated and functionally an...
-
Article
Open AccessEGR-1/ASPP1 inter-regulatory loop promotes apoptosis by inhibiting cyto-protective autophagy
The decrease of ASPP1 (Apoptosis-Stimulating Protein of p53 1), a known p53 activator, has been linked to carcinogenesis and the cytotoxic resistance in various cancers, yet the underlying mechanisms of ASPP1 ...
-
Article
Open AccessUpregulation of MiR-205 under hypoxia promotes epithelial–mesenchymal transition by targeting ASPP2
The epithelial–mesenchymal transition (EMT) is one of the crucial procedures for cancer invasion and distal metastasis. Despite undergoing intensive studies, the mechanisms underlying EMT remain to be complete...
-
Article
Open AccessEmbedded mobile crowd service systems based on opportunistic geological grid and dynamical segmentation
In order to solve these problems such as the demand of geographic information service and the short life of the embedded system, as well as network collapse, and so on, the embedded mobile crowd service system...
