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Sp1 is a key regulator of the PDGF β-receptor transcription

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  1. Article

    Open Access

    Differential acute impact of therapeutically effective and overdose concentrations of lithium on human neuronal single cell and network function

    Lithium salts are used as mood-balancing medication prescribed to patients suffering from neuropsychiatric disorders, such as bipolar disorder and major depressive disorder. Lithium salts cross the blood-brain...

    Julia Izsak, Henrik Seth, Margarita Il**, Stephan Theiss… in Translational Psychiatry (2021)

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  2. Article

    Open Access

    Identification of candidate genetic variants and altered protein expression in neural stem and mature neural cells support altered microtubule function to be an essential component in bipolar disorder

    Identification of causative genetic variants leading to the development of bipolar disorder (BD) could result in genetic tests that would facilitate diagnosis. A better understanding of affected genes and path...

    Katarina Truvé, Toshima Z. Parris, Dzeneta Vizlin-Hodzic… in Translational Psychiatry (2020)

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  3. Article

    Open Access

    TLX—Its Emerging Role for Neurogenesis in Health and Disease

    The orphan nuclear receptor TLX, also called NR2E1, is a factor important in the regulation of neural stem cell (NSC) self-renewal, neurogenesis, and maintenance. As a transcription factor, TLX is vital for th...

    Praveen K. Sobhan, Keiko Funa in Molecular Neurobiology (2017)

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  4. Article

    Open Access

    The Roles of PDGF in Development and During Neurogenesis in the Normal and Diseased Nervous System

    The four platelet-derived growth factor (PDGF) ligands and PDGF receptors (PDGFRs), α and β (PDGFRA, PDGFRB), are essential proteins that are expressed during embryonic and mature nervous systems, i.e., in neu...

    Keiko Funa, Masakiyo Sasahara in Journal of Neuroimmune Pharmacology (2014)

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