4 Result(s)
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Article
Open AccessDifferential acute impact of therapeutically effective and overdose concentrations of lithium on human neuronal single cell and network function
Lithium salts are used as mood-balancing medication prescribed to patients suffering from neuropsychiatric disorders, such as bipolar disorder and major depressive disorder. Lithium salts cross the blood-brain...
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Article
Open AccessIdentification of candidate genetic variants and altered protein expression in neural stem and mature neural cells support altered microtubule function to be an essential component in bipolar disorder
Identification of causative genetic variants leading to the development of bipolar disorder (BD) could result in genetic tests that would facilitate diagnosis. A better understanding of affected genes and path...
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Article
Expression of transforming growth factor-β1, 2, 3 isoforms and type I and II receptors in acute focal cerebral ischemia: an immunohistochemical study in rat after transient and permanent occlusion of middle cerebral artery
Transforming growth factor beta (TGF-β) is involved in the modulation of cell growth, differentiation and repair following injury of various organs. Previous studies on human autopsy material have indicated t...
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Article
Expression of various TGF-β isoforms and type I receptor in necrotizing human brain lesions
It is known that transforming growth factor beta (TGF-β) is involved in the modulation of cell growth, differentiation, and repair following injury. We performed an immunohistochemical study of human brain au...
