4 Result(s)
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Article
Keiko Funa
Biomedicine
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Article
PDGF and its receptors following facial nerve axotomy in rats: expression in neurons and surrounding glia
We investigated the expression of platelet-derived growth factor (PDGF) and its receptors in rat facial nuclei following axotomy by in situ hybridization and immunohistochemistry. Facial nuclei were examined o...
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Specific effects of platelet derived growth factor (PDGF) on fetal rat and human dopaminergic neurons in vitro
The neurotrophic effects of the BB isoform of platelet-derived growth factor (PDGF) on rat and human fetal mesencephalic dopaminergic neurons have been characterized in vitro. A dose-response analysis demonstr...
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Open AccessThe Roles of PDGF in Development and During Neurogenesis in the Normal and Diseased Nervous System
The four platelet-derived growth factor (PDGF) ligands and PDGF receptors (PDGFRs), α and β (PDGFRA, PDGFRB), are essential proteins that are expressed during embryonic and mature nervous systems, i.e., in neu...
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Article
Open AccessTLX—Its Emerging Role for Neurogenesis in Health and Disease
The orphan nuclear receptor TLX, also called NR2E1, is a factor important in the regulation of neural stem cell (NSC) self-renewal, neurogenesis, and maintenance. As a transcription factor, TLX is vital for th...
