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    Article

    Photocatalytic hydrofluoroalkylation of alkenes with carboxylic acids

    Incorporation of fluoroalkyl motifs in pharmaceuticals can enhance the therapeutic profiles of the parent molecules. The hydrofluoroalkylation of alkenes has emerged as a promising route to diverse fluoroalkyl...

    Kang-Jie Bian, Yen-Chu Lu, David Nemoto Jr, Shih-Chieh Kao in Nature Chemistry (2023)

  2. Article

    Publisher Correction: Photocatalytic hydrofluoroalkylation of alkenes with carboxylic acids

    Kang-Jie Bian, Yen-Chu Lu, David Nemoto Jr, Shih-Chieh Kao in Nature Chemistry (2023)

  3. Article

    Open Access

    Photochemical diazidation of alkenes enabled by ligand-to-metal charge transfer and radical ligand transfer

    Vicinal diamines are privileged synthetic motifs in chemistry due to their prevalence and powerful applications in bioactive molecules, pharmaceuticals, and ligand design for transition metals. With organic di...

    Kang-Jie Bian, Shih-Chieh Kao, David Nemoto Jr., **ao-Wei Chen in Nature Communications (2022)

  4. Article

    Open Access

    Asymmetric construction of allylicstereogenic carbon center featuring atrifluoromethyl group via enantioselective reductive fluoroalkylation

    Emerging as a powerful tool for lead optimization in pharmaceutical research and development, to develop the facile, general protocols that allows the incorporation of fluorine-containing motif in drug candida...

    Ruo-**ng **, Bing-Bing Wu, Kang-Jie Bian, Jian-Liang Yu in Nature Communications (2022)

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    Article

    Visible-light-induced, autopromoted nickel-catalyzed three-component arylsulfonation of 1,3-enynes and mechanistic insights

    A light-induced, nickel-catalyzed three-component arylsulfonation of 1,3-enynes in the absence of photocatalyst is reported. This methodology exhibited mild conditions, broad scope and high efficiency, and its...

    Duo-Duo Hu, Qian Gao, **g-Cheng Dai, Ru Cui, Yuan-Bo Li in Science China Chemistry (2022)