17 Result(s)
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Article
Kailash Singh
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Article
Enhancing the Hydrophobicity and Surface Roughness of Synthesized PVDF Membrane Using Evaporation and Non-solvent-Induced Phase Separation
This study focuses on the synthesis of a PVDF membrane using DMAc as the solvent through a combination of evaporation-induced phase separation (EIPS) and non solvent-induced phase separation (NIPS) techniques....
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Open AccessAssessing the effectiveness of Interleukin-2 therapy in experimental type 1 diabetes
Much focus of immunotherapy for type 1 diabetes (T1D) has been devoted on selectively boosting regulatory T (Treg) cells using low dose IL-2 due to their constitutive expression of IL-2Rα, CD25. However, sever...
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Open AccessAstrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation
The ability of immune-modulating biologics to prevent and reverse pathology has transformed recent clinical practice. Full utility in the neuroinflammation space, however, requires identification of both effec...
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Open AccessPurification and identification of a surfactin biosurfactant and engine oil degradation by Bacillus velezensis KLP2016
Engine oil used in automobiles is a threat to soil and water due to the recalcitrant properties of its hydrocarbons. It pollutes surrounding environment which affects both flora and fauna. Microbes can degrade...
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Dynamic Neural Network Based Sensing and Controlling a Reactive Distillation Column Having Inverse Response
The inverse response is one of the obstacles in control studies which leads to instability and causes difficulty in a control system. In this paper, a dynamic neural network based estimator and controller are ...
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Development of heat and mass transfer correlations and recovery calculation for HCl–water azeotropic separation using air gap membrane distillation
In the present work, the air gap membrane distillation (AGMD) process has been experimentally studied for the separation of aqueous HCl azeotropic (20.2 wt% HCl) mixture. A test cell AGMD module equipped with ...
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Open AccessThe Cdh5-CreERT2 transgene causes conditional Shb gene deletion in hematopoietic cells with consequences for immune cell responses to tumors
The tamoxifen-responsive conditional Cdh5-CreERT2 is commonly used for endothelial cell specific conditional deletion of loxP-flanked gene sequences. To address the role of endothelial cell Shb gene for B16F10 me...
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Open AccessOverexpression of heparanase enhances T lymphocyte activities and intensifies the inflammatory response in a model of murine rheumatoid arthritis
Heparanase is an endo-glucuronidase that degrades heparan sulfate chains. The enzyme is expressed at a low level in normal organs; however, elevated expression of heparanase has been detected in several inflam...
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Open AccessAmino acid substitutions V63I or A37S/I61T/V63I/V100A in the PA N-terminal domain increase the virulence of H7N7 influenza A virus
The PA N-terminal domain (PA-Nter) is essential for viral transcription and replication. Here we identified PA-Nter substitutions A37S, I61T, V63I and V100A in recently emerged avian influenza A viruses (IAVs)...
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Open AccessA novel small-molecule inhibitor of influenza A virus acts by suppressing PA endonuclease activity of the viral polymerase
The RNA-dependent RNA polymerase of influenza A virus comprises conserved and independently-folded subdomains with defined functionalities. The N-terminal domain of the PA subunit (PAN) harbors the endonuclease f...
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Simulation-Based Artificial Neural Network Predictive Control of BTX Dividing Wall Column
For the separation of ternary liquid mixture, use of dividing wall column is one of the nonconventional techniques in the field of liquid separation by thermal process. Benzene, toluene, and o-xylene have been se...
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Open AccessInterleukin-35 administration counteracts established murine type 1 diabetes – possible involvement of regulatory T cells
The anti-inflammatory cytokine IL-35 is produced by regulatory T (Treg) cells to suppress autoimmune and inflammatory responses. The role of IL-35 in type 1 diabetes (T1D) remains to be answered. To elucidate ...
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Open AccessConcomitant analysis of Helios and Neuropilin-1 as a marker to detect thymic derived regulatory T cells in naïve mice
Regulatory T (Treg) cells are characterized by the expression of CD4, CD25 and the intracellular Foxp3. However, these markers do not indicate whether Treg cells are thymic derived Treg (tTreg) cells or periph...
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Climatically induced levee break and flood risk management of the Gorakhpur region, Rapti River basin, Ganga Plain, India
A densely populated city, Gorakhpur, located on the bank of Rapti river in the Ganga plain, is frequently affected by flooding. The Rapti river exhibits narrow channel within wide valley, channel bars, natural...
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Volumetric, Compressibility, and Surface Tension Studies on Micellization Behavior of SDS in Aqueous Medium: Effect of Sugars
The densities \((d)\) ( ...
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A review on reactive adsorption for potential environmental applications
The aim of this paper is to present a critical review on reactive adsorption processes. The impact of surface modification on adsorption behavior of various adsorbents in context of reactive adsorption has bee...
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Effect of prilled urea and modified urea materials on yield and quality of geranium (Pelargonium graveolens L. Her.)
Two field experiments were conducted to study the effect of prilled urea, neem cake coated urea, dicyandiamide treated urea and urea supergranules applied to a perennial aromatic herb, geranium (Pelargonium grave...
