26 Result(s)

Article

Multiplication of human-derivedPneumocystis carinii in severe combined immunodeficient (SCID) mice

clinically healthy SCID mice were infected intratracheally withPneumocystis carinii (PC) of human origin. The data obtained provides unambiguous evidence that progressive multiplication of PC organisms of human o...

K. K. Sethi in Experientia (1992)

Article

Phenotypic heterogeneity of cerebrospinal fluid-derived HIV-specific and HLA-restricted cytotoxic T-cell clones

A variety of clinical syndromes, including AIDS and neurological disorders, may follow as a consequence of infection with the human immunodeficiency virus type 1 (HIV-1)^1–4. It is not yet clear, however, to what ...

K. K. Sethi, H. Näher, I. Stroehmann in Nature (1988)

Article

Electron microscope observations on the interaction ofMycoplasma fermentans withTrichomonas vaginalis

Cultures ofTrichomonas vaginalis were found to be contaminated withMycoplasma fermentans. By means of electron microscopy the interaction between the prokaryotic organisms and the trichomonads was examined. Cells...

E. Scholtyseck, J. Teras, I. Kasakova, K. K. Sethi in Zeitschrift für Parasitenkunde (1985)

Article

Topographical localization of distinct antigenic domains ofToxoplasma gondii with the aid of monoclonal antibodies

In the present study, a panel of six individual hybridoma derived antibodies produced against the BK strain ofToxoplasma gondii were evaluated for their reactivity in an immunofluorescence test. Each of the six m...

K. K. Sethi, Y. Omata, H. Brandis in Zeitschrift für Parasitenkunde (1984)

Article

Human T-cell cultures from virus-sensitized donors can mediate virus-specific and HLA-restricted cell lysis

Human cells infected with viruses such as herpes simplex virus (HSV) or Epstein–Barr virus (EBV) become susceptible to the lytic action of a distinct population of lymphocytes termed natural killer (NK) cells ...

K. K. Sethi, I. Stroehmann, H. Brandis in Nature (1980)

Article

In vitro acquisition of resistance against herpes simplex virus by permissive murine macrophages

This study has documented that peritoneal macrophages (PM) from adult mice of strains DBA/2J, BALB/c and AKR can support productive replication of herpes simplex virus (HSV) strains Thea and Haase. Simian viru...

K. K. Sethi, H. Brandis in Archives of Virology (1979)

Article

Induction of virus specific and H-2 restricted cytotoxic T cells by UV inactivated murine cytomegalovirus

Infection of C3H mice with live or UV-inactivated murine cytomegalovirus (MCMV) was able to generate population(s) of lymphocytes in the spleen (CTL) which could exert a lytic effect against L cells infected w...

K. K. Sethi, H. Brandis in Archives of Virology (1979)

Article

Presence of viruses in a strain ofMycoplasma pulmonis

Filtrates prepared from heavily grown agar cultures ofM. pulmonis strain Negroni-52 formed plaques on lawns ofA. laidlawii strain JA1 but not on those ofM. pulmonis strains Ash or Negroni-52. The plaque-forming a...

A. A. Rahman, K. K. Sethi in Experientia (1979)

Article

Interferon enhances T cell mediated cytotoxicity of H-2 compatible target cells infected with UV-inactivated herpes simplex virus

Mouse L-cells infected with UV-inactivated HSV could serve as suitable targets for monitoring H-2 restricted cytotoxicity mediated by HSV-immune T cells. Cytotoxic potential of immune T cells for H-2 compatibl...

K. K. Sethi, H. Brandis in Archives of Virology (1978)

Article

Intracellular behaviour ofLeishmania enriettii within murine macrophages

Both promastigotes and amastigotes ofLeishmania enriettii were readily ingested by mouse peritoneal macrophages (MPM). Promastigotes after their entry within MPM were rapidly immobilized and their multiplication ...

A. A. Rahman, K. K. Sethi in Experientia (1978)

Article

Introduction of mouse L cell nucleus into heterologous mammalian cells

HARRIS¹ first achieved the introduction of a chick erythrocyte nucleus into other nucleated mammalian cells, without any detectable incorporation of chick erythrocyte cytoplasma, using inactivated Sendai virus. S...

K. K. SETHI, H. BRANDIS in Nature (1974)

Article

Neuraminidase Induced Loss in the Transplantability of Murine Leukaemia L 1210, Induction of Immunoprotection and the Transfer of Induced Immunity to Normal DBA/2 Mice by Serum and Peritoneal Cells

Leukaemia L 1210 cells preincubated in vitro with neuraminidase preparations derived either from Vibrio cholerae (VCN) or Clostridium perfringens (CPN) lost their i.p. transplantability for normal DBA/2 mice. Thi...

K K Sethi, H Brandis in British Journal of Cancer (1973)

Article

Proteolytic activity of Cryptococcus neoformans against human plasma proteins

Although Cryptococcus neoformans is not regarded as proteolytic, the sensitive technique of immunoelectrophoresis has demonstrated its ability to degrade human α₂HS-glycoprotein and split up human as also pure ca...

H. E. Müller, K. K. Sethi in Medical Microbiology and Immunology (1972)

Article

Über die Aktivitätssteigerung mikrobieller Neuraminidasen bei niedrigen Wasserstoffperoxid-Konzentrationen

The activity of bacterial neuraminidases can be influenced by H₂O₂ secreted by some organisms. Thus, at low H₂O₂ concentrations (0.002–0.01%), an increase of neuraminidase activities was observed, whereas at conc...

H. E. Müller, K. K. Sethi in Experientia (1972)

Article

Mycoplasma interactions with cell cultures, uncultured living cells and the problems posed by their presence in tissue cultures

The presence of mycoplasmas in tissue cultures has created many problems for investigators employing cell cultures, especially with respect to the interpretation of the results. It was partly because of these ...

K. K. Sethi, M. Teschner in Klinische Wochenschrift (1972)

Article

Über das Vorkommen von Neuraminidase beiMycoplasma gallisepticum

The presence of neuraminidase activity in aMycoplasma gallisepticum strain was demonstrated by colorimetric determination of free N-acetylneuraminic acid released from various neuraminic acid containing substrate...

H. E. Müller, K. K. Sethi in Medical Microbiology and Immunology (1972)

Article

Killing of mycoplasmas by the antibodies to foreign antigens acquired by the organisms from the growth medium

The incubation of rabbit anti-horse serum (anti-HS) with mycoplasmas (represented byMycoplasma gallisepticum andMycoplasma pneumoniae strains) grown in presence of 20% horse serum resulted in significant killing ...

K. K. Sethi, H. Brandis in Medical Microbiology and Immunology (1972)

Article

International mycoplasma symposium 6/7th September 1971 in Mainz Summaries of the papers

W. Bredt, J. Maniloff, J. Das, D. Quinlan… in Medical Microbiology and Immunology (1972)

Article

Interaction between mycoplasmas and Ehrlich ascites tumor cells

Es wurde gezeigt, dass die Adsorption von Mycoplasmen an Ehrlich Ascites-Tumorzellen an das Vorhandensein von neuraminidase-empfindlichen Zellrezeptoren gebunden ist.

K. K. Sethi, H. Brandis in Experientia (1970)