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  1. No Access

    Article

    Synergistic cytotoxicity of oncolytic reovirus in combination with cisplatin–paclitaxel doublet chemotherapy

    Oncolytic reovirus is currently under active investigation in a range of tumour types. Early phase studies have shown that this agent has modest monotherapy efficacy and its future development is likely to foc...

    V Roulstone, K Twigger, S Zaidi, T Pencavel, J N Kyula, C White… in Gene Therapy (2013)

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    Article

    Reovirus and other oncolytic viruses for the targeted treatment of cancer

    In the last 50 years, there have been a number of anecdotal reports of viral infections causing transient cancer remissions in patients with advanced disease. However, during the last decade, these reports hav...

    L. Vidal, T. A. Yap, C. L. White, K. Twigger, M. Hingorani, V. Agrawal… in Targeted Oncology (2006)