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Article
Open AccessA large deletion conferring pale green leaves of maize
The structural basis of chloroplast and the regulation of chloroplast biogenesis remain largely unknown in maize. Gene mutations in these pathways have been linked to the abnormal leaf color phenotype observed...
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Article
Improving knee osteoarthritis classification using multimodal intermediate fusion of X-ray, MRI, and clinical information
The most common form of arthritis is osteoarthritis (OA) which often affects the knee joint. Recent studies are utilizing convolution neural networks (CNNs) to automatically classify OA severity. These deep le...
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Article
Automated cell division classification in early mouse and human embryos using convolutional neural networks
During in vitro fertilization (IVF), the timing of cell divisions in early human embryos is a key predictor of embryo viability. Recent developments in time-lapse microscopy (TLM) have allowed us to observe ce...
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Article
Open AccessSpin transport in insulators without exchange stiffness
The discovery of new materials that efficiently transmit spin currents has been important for spintronics and material science. The electric insulator Gd3Ga5O12 (GGG), a standard substrate for growing magnetic fi...
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Article
Open AccessOver-expression of microRNA-494 up-regulates hypoxia-inducible factor-1 alpha expression via PI3K/Akt pathway and protects against hypoxia-induced apoptosis
Hypoxia-inducible factor-1 alpha (HIF-1α) is one of the key regulators of hypoxia/ischemia. MicroRNA-494 (miR-494) had cardioprotective effects against ischemia/reperfusion (I/R)-induced injury, but its functi...
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Article
Open AccessThe role of HIF-1 in up-regulating MICA expression on human renal proximal tubular epithelial cells during hypoxia/reoxygenation
Human major histocompatibility complex class I-related chain A (MICA) plays a dual role in adaptive and innate immune responses. Increasing evidence demonstrates that MICA is closely correlated with acute and ...
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Article
Open AccessPeripheral blood T Regulatory cell counts may not predict transplant rejection
Recent evidence shows that allograft survival rates show a positive correlation with the number of circulating T regulatory cells (Tregs). This study investigated both the number and the cytokine profiles exhi...
