1 Result(s)

Article

Identification of the major photodegradant in metronidazole by LC-PDA-MS and its reveal in compendial methods

Metronidazole in aqueous solution is sensitive to light and UV irradiation, leading to the formation of N-(2-hydroxyethyl)-5-methyl-l,2,4-oxadiazole-3-carboxamide. This is revealed here by liquid chromatography w...

Mei-Ling Chen, Hong-**a Xu, Wei-Feng Yuan, Sui-Hong Zhao, Xue Li… in Scientific Reports (2022)