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  1. No Access

    Article

    Are there new relevant therapeutic endpoints in the modern era of the BCR::ABL1 tyrosine kinase inhibitors in chronic myeloid leukemia?

    Hagop Kantarjian, Susan Branford, Massimo Breccia, Jorge Cortes, Fadi G. Haddad in Leukemia (2024)

  2. Article

    Open Access

    Dose modification dynamics of ponatinib in patients with chronic-phase chronic myeloid leukemia (CP-CML) from the PACE and OPTIC trials

    Ponatinib, the only approved all known-BCR::ABL1 inhibitor, is a third-generation tyrosine-kinase inhibitor (TKI) designed to inhibit BCR::ABL1 with or without any single resistance mutation, including T315I, ...

    Elias Jabbour, Jane Apperley, Jorge Cortes, Delphine Rea, Michael Deininger in Leukemia (2024)

  3. Article

    Open Access

    Safety and efficacy of talacotuzumab plus decitabine or decitabine alone in patients with acute myeloid leukemia not eligible for chemotherapy: results from a multicenter, randomized, phase 2/3 study

    Talacotuzumab, a humanized anti-CD123 monoclonal antibody, was evaluated in combination with decitabine in elderly patients with acute myeloid leukemia (AML) not eligible for intensive chemotherapy. A multicen...

    Pau Montesinos, Gail J. Roboz, Claude-Eric Bulabois, Marion Subklewe in Leukemia (2021)

  4. No Access

    Article

    Laying the foundation for genomically-based risk assessment in chronic myeloid leukemia

    Outcomes for patients with chronic myeloid leukemia (CML) have substantially improved due to advances in drug development and rational treatment intervention strategies. Despite these significant advances ther...

    Susan Branford, Dennis Dong Hwan Kim, Jane F. Apperley, Christopher A. Eide in Leukemia (2019)

  5. No Access

    Article

    Response kinetics and factors predicting survival in core-binding factor leukemia

    Prajwal Boddu, Christopher Gurguis, David Sanford, Jorge Cortes, Mary Akosile in Leukemia (2018)