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Isolation of mitochondria-derived mitovesicles and subpopulations of microvesicles and exosomes from brain tissues

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  1. Article

    Open Access

    Mitovesicles secreted into the extracellular space of brains with mitochondrial dysfunction impair synaptic plasticity

    Hypometabolism tied to mitochondrial dysfunction occurs in the aging brain and in neurodegenerative disorders, including in Alzheimer’s disease, in Down syndrome, and in mouse models of these conditions. We ha...

    Pasquale D’Acunzo, Elentina K. Argyrousi… in Molecular Neurodegeneration (2024)

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  2. Article

    Open Access

    Cocaine Modulates the Neuronal Endosomal System and Extracellular Vesicles in a Sex-Dependent Manner

    In multiple neurodevelopmental and neurodegenerative disorders, endosomal changes correlate with changes in exosomes. We examined this linkage in the brain of mice that received cocaine injections for two week...

    Bryana R. Barreto, Pasquale D’Acunzo, Jonathan M. Ungania… in Neurochemical Research (2022)

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