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    BMD188, A novel hydroxamic acid compound, demonstrates potent anti-prostate cancer effectsin vitro andin vivo by inducing apoptosis: requirements for mitochondria, reactive oxygen species, and proteases

    A newly synthesized cyclic hydroxamic acid compound, BMD188 [cis-l-hydroxy-4-(l-naphthyl)-6-oc-tylpiperidine-2-one], was found to induce the apoptotic death of cultured prostate cancer cells by activating casp...

    Dean G Tang, Li Li, Zhenyu Zhu, Bindu Joshi… in Pathology & Oncology Research (1998)