11 Result(s)
within
English
Science, Humanities and Social Sciences, multidisciplinary
Jiali Han
Article
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Article
Open AccessGenome-wide association meta-analysis identifies 29 new acne susceptibility loci
Acne vulgaris is a highly heritable skin disorder that primarily impacts facial skin. Severely inflamed lesions may leave permanent scars that have been associated with long-term psychosocial consequences. Her...
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Open AccessGenome-wide meta-analysis identifies eight new susceptibility loci for cutaneous squamous cell carcinoma
Cutaneous squamous cell carcinoma (SCC) is one of the most common cancers in the United States. Previous genome-wide association studies (GWAS) have identified 14 single nucleotide polymorphisms (SNPs) associa...
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Open AccessPublisher Correction: Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways
The original version of this Article contained errors in the spelling of the authors Fan Liu and M. Arfan Ikram, which were incorrectly given as Fan Lui and Arfan M. Ikram. In addition, the original version of...
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Open AccessNovel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways
The total number of acquired melanocytic nevi on the skin is strongly correlated with melanoma risk. Here we report a meta-analysis of 11 nevus GWAS from Australia, Netherlands, UK, and USA comprising 52,506 i...
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Open AccessGenome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure
The skin’s tendency to sunburn rather than tan is a major risk factor for skin cancer. Here we report a large genome-wide association study of ease of skin tanning in 176,678 subjects of European ancestry. We ...
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Open AccessPreliminary effectiveness of breast cancer screening among 1.22 million Chinese females and different cancer patterns between urban and rural women
To determine the preliminary effectiveness of breast cancer screening among Chinese females, 1226714 women aged 35–69 years first received clinical breast examinations. Urban women with suspected cancer receiv...
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Open AccessTissue-specific Co-expression of Long Non-coding and Coding RNAs Associated with Breast Cancer
Inference of the biological roles of lncRNAs in breast cancer development remains a challenge. Here, we analyzed RNA-seq data in tumor and normal breast tissue samples from 18 breast cancer patients and 18 hea...
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Open AccessGenome-wide association study identifies 14 novel risk alleles associated with basal cell carcinoma
Basal cell carcinoma (BCC) is the most common cancer worldwide with an annual incidence of 2.8 million cases in the United States alone. Previous studies have demonstrated an association between 21 distinct ge...
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Open AccessGenome-wide association study identifies novel susceptibility loci for cutaneous squamous cell carcinoma
Cutaneous squamous cell carcinoma represents the second most common cutaneous malignancy, affecting 7–11% of Caucasians in the United States. The genetic determinants of susceptibility to cutaneous squamous ce...
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Open AccessNew loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk
To increase our understanding of the genetic basis of adiposity and its links to cardiometabolic disease risk, we conducted a genome-wide association meta-analysis of body fat percentage (BF%) in up to 100,716...
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Open AccessGenome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility
Psoriasis is a common inflammatory skin disease with complex genetics and different degrees of prevalence across ethnic populations. Here we present the largest trans-ethnic genome-wide meta-analysis (GWMA) of...
