8 Result(s)
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Article
Jasper Boeddinghaus
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Article
Open AccessIncreased afterload induces pathological cardiac hypertrophy: a new in vitro model
Increased afterload results in ‘pathological’ cardiac hypertrophy, the most important risk factor for the development of heart failure. Current in vitro models fall short in deciphering the mechanisms of hyper...
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Gender-specific uncertainties in the diagnosis of acute coronary syndrome
It is unknown whether higher rates of delayed diagnosis and misdiagnosis of acute coronary syndrome (ACS) in women might have contributed to the poorer outcome of women.
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Early diagnosis of acute myocardial infarction in patients with mild elevations of cardiac troponin
The early diagnosis of acute myocardial infarction (AMI) in patients with mild elevations of high-sensitivity cardiac troponin (hs-cTn) is a challenge. It is unclear whether copeptin, a marker of endogenous st...
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Article
Automatically computed ECG algorithm for the quantification of myocardial scar and the prediction of mortality
Myocardial scar is associated with adverse cardiac outcomes. The Selvester QRS-score was developed to estimate myocardial scar from the 12-lead ECG, but its manual calculation is difficult. An automatically co...
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Article
Obesity paradox and perioperative myocardial infarction/injury in non-cardiac surgery
The impact of obesity on the incidence of perioperative myocardial infarction/injury (PMI) and mortality following non-cardiac surgery is not well understood.
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Open AccessMachine learning for diagnosis of myocardial infarction using cardiac troponin concentrations
Although guidelines recommend fixed cardiac troponin thresholds for the diagnosis of myocardial infarction, troponin concentrations are influenced by age, sex, comorbidities and time from symptom onset. To imp...
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Open AccessCombining glucose and high-sensitivity cardiac troponin in the early diagnosis of acute myocardial infarction
Glucose is a universally available inexpensive biomarker, which is increased as part of the physiological stress response to acute myocardial infarction (AMI) and may therefore help in its early diagnosis. To ...
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Open AccessGRACE scores or high-sensitivity troponin for timing of coronary angiography in non-ST-elevation acute coronary syndromes
The GRACE risk score is generically recommended by guidelines for timing of invasive coronary angiography without stating which score should be used. The aim was to determine the diagnostic performance of diff...
