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Article
Endoscopic drainage with local infusion of antibiotics to avoid necrosectomy of infected walled-off necrosis
Current treatment of infected pancreatic necrosis (IPN) follows a step-up approach. Our group designed a step-up protocol that associates endoscopic drainage with local infusion of antibiotics through transmur...
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Article
Open AccessDifferences in In Vitro Properties of Pancreatin Preparations for Pancreatic Exocrine Insufficiency as Marketed in Russia and CIS
Pancreatic enzyme-replacement therapy (PERT), provided as pancreatin to patients with pancreatic exocrine insufficiency (PEI), is considered an essential substitute for the pivotal physiological function the p...
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Article
Open AccessExocrine Pancreatic Insufficiency Following Acute Pancreatitis: Systematic Review and Meta-Analysis
The epidemiology of exocrine pancreatic insufficiency (EPI) after acute pancreatitis (AP) is uncertain. We sought to determine the prevalence, progression, etiology and pancreatic enzyme replacement therapy (P...
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Article
Chronic pancreatitis
Chronic pancreatitis is defined as a pathological fibro-inflammatory syndrome of the pancreas in individuals with genetic, environmental and/or other risk factors who develop persistent pathological responses ...
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Article
Potential for Screening for Pancreatic Exocrine Insufficiency Using the Fecal Elastase-1 Test
The early diagnosis of pancreatic exocrine insufficiency (PEI) is hindered because many of the functional diagnostic techniques used are expensive and require specialized facilities, which prevent their widesp...
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Article
Clinical Response (Remission of Symptoms) in Erosive and Non-Erosive Gastro-Oesophageal Reflux Disease
Complete remission of symptoms and prevention of symptomatic recurrence are among the main therapeutic aims in gastro-oesophageal reflux disease (GORD). In this context, a potent pharmacologic inhibition of ga...
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Article
Early antibiotic treatment (prophylaxis) of septic complications in severe acute necrotizing pancreatitis: a prospective, randomized, multicenter study comparing two regimens with imipenem-cilastatin
We compared two imipenem regimens for prevention of septic complications in patients with severe acute necrotizing pancreatitis (ANP).
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Article
Hyperlipidemia in acute pancreatitis
Whether hyperlipidemia is a pre-existing metabolic disorder or a consequence of acute pancreatitis is still debated. Mild to moderate elevation of serum triglyceride levels are likely to be an epiphenomenon of...
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Article
Assessment of the fibrogenetic activity in chronic pancreatitis
Determination of circulating levels of extracellular matrix components has been proposed as a reliable method to assess the activity of fibrogenetic processes. Therefore, we aimed to analyze circulating levels...
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Article
Prognostic factors in acute pancreatitis