41 Result(s)
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Article
J. B. Griffiths
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The stability of Killing–Cauchy horizons in colliding plane wave space-times
It is confirmed rigorously that the Killing–Cauchy horizons, which sometimes occur in space-times representing the collision and subsequent interaction of plane gravitational waves in a Minkowski background, are
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Null Limits of the C-Metric
The C-metric is usually understood as describing two black holes which accelerate in opposite directions under the action of some conical singularity. Here, we examine all the solutions of this type which repr...
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Null Limits of Generalised Bonnor-Swaminarayan Solutions
The Bonnor-Swaminarayan solutions are boost-rotation symmetric space-times which describe the motion of pairs of accelerating particles which are possibly connected to strings (struts). In an explicit and unif...
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An integrated strategy for the process development of a recombinant antibody-cytokine fusion protein expressed in BHK cells
Recombinant fusion proteins offer important new therapeutic approaches for the future. This report describes the use of three different genetic strategies (i.e. “mono-”, “bi-” and “tri-cistronic” vectors) to ...
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The Extensions of Gravitational Soliton Solutions with Real Poles
We analyse vacuum gravitational“soliton” solutions with real poles in thecosmological context. It is well known that thesesolutions contain singularities on certain nullhypersurfaces. Using a Kasner seed solut...
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Perfect fluid space-times with a two-dimensional orthogonally transitive group of homothetic motions
We use theghp formalism to obtain perfect fluid space-times with a two-dimensional and orthogonally transitive group of proper homothetic motionsH 2, with the additional condition that the four-velocity of the fl...
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A class of plane symmetric dust solutions
A class of plane symmetric solutions containing dust is considered. It is argued that, however inhomogeneous the mass distribution, matter on each plane of symmetry has no net attraction to matter on other pla...
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Book reviews
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Book review
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Physical interpretation of vacuum solutions of Einstein's equations. Part II. Time-dependent solutions
The study of interpretations of the vacuum solutions of Einstein's field equations is continued by considering some well known time-dependent solutions. Among these are metrics representing accelerating partic...
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Expression of recombinant antibody and secreted alkaline phosphatase in mammalian cells. Influence of cell line and culture system upon production kinetics
The growth and productivity of an Sp2/0 cell line, F3b10, expressing a recombinant antibody (rAb) and BHK21 cells expressing either the same rAb from the same plasmids (BHK.IgG) or secreted alkaline phosphatas...
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Cultural and physiological factors affecting expression of recombinant proteins
The variability in expression of recombinant proteins has been analyzed with regard to (a) comparison of clones from the same transfection experiment; (b) comparison of the same genetic construct in different ...
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Colliding plane gravitational waves with colinear polarization
The colliding plane wave problem is considered using an unconventional coordinate system. This permits a complete solution to be explicitly stated for the general case of arbitrary approaching waves with const...
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Investigation of parameters affecting a fixed bed bioreactor process for recombinant cell lines
A BHK 21 cell line expressing a recombinant antibody was grown in a fixed bed reactor (FBR) system using a porous support made of Siran glass beads. The contribution of five process variables (bead and inoculu...
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Maximisation of perfusion systems and process comparison with batch-type cultures
A comparison of cell yields and monoclonal antibody productivity from the same hybridoma has been made in a wide range of cell bioreactors including both batch and continuous perfusion cultures. The most produ...
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The effect of bioreactor configuration on production of HIV and cell-virus interaction
In an attempt to establish a bioreactor system for generation of HIV that is practicable, efficient, biologically contained, and capable of scale up, the production of two strains of this virus was examined in...
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A new class of exact solutions of the vacuum quadratic Poincaré gauge field theory
A class of algebraically special exact solutions of the vacuum quadratic Poincaré gauge field theory is presented. These solutions are of type III and type N and have a nonexpanding, shear-free and twist-free ...
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Use of lactate dehydrogenase release to assess changes in culture viability
This study reports the use of lactate dehydrogenase release to monitor changes in culture viability in flask culture and fixed bed, porosphere bioreactor systems. Lactate dehydrogenase release shows good agree...
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The application of spin coefficient techniques in the vacuum quadratic Poincaré gauge field theory
The vacuum field equations of the quadratic Poincaré gauge field theory are expressed in the spin coefficient formalism of Newman and Penrose. These are differential identities involving curvature and torsion ...
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Colliding plane gravito-electromagnetic waves
The collision and interaction of plane electromagnetic waves is considered. Field equations are formulated and the appropriate boundary conditions are described in detail. A solution-generating technique is de...
