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    Article

    An integrated strategy for the process development of a recombinant antibody-cytokine fusion protein expressed in BHK cells

    Recombinant fusion proteins offer important new therapeutic approaches for the future. This report describes the use of three different genetic strategies (i.e. “mono-”, “bi-” and “tri-cistronic” vectors) to ...

    C. Burger, M. J. T. Carrondo, H. Cruz, M. Cuffe in Applied Microbiology and Biotechnology (1999)

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    Article

    Expression of recombinant antibody and secreted alkaline phosphatase in mammalian cells. Influence of cell line and culture system upon production kinetics

    The growth and productivity of an Sp2/0 cell line, F3b10, expressing a recombinant antibody (rAb) and BHK21 cells expressing either the same rAb from the same plasmids (BHK.IgG) or secreted alkaline phosphatas...

    A. J. Racher, J. L. Moreira, P. M. Alves in Applied Microbiology and Biotechnology (1994)