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Fludarabine and cyclophosphamide in combination with alemtuzumab in patients with primary high-risk, relapsed or refractory chronic lymphocytic leukemia

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    Open Access

    Lamin B1 regulates somatic mutations and progression of B-cell malignancies

    Somatic hypermutation (SHM) is a pivotal process in adaptive immunity that occurs in the germinal centre and allows B cells to change their primary DNA sequence and diversify their antigen receptors. Here, we ...

    T Klymenko, J Bloehdorn, J Bahlo, S Robrecht, G Akylzhanova, K Cox in Leukemia (2018)