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Article
Electric cell death
A clear picture of how and why cells inevitably lose viability is still lacking. A dynamical systems view of starving bacteria points to a continuous energy expenditure needed for maintaining the right osmotic...
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Open AccessMacroscopic quorum sensing sustains differentiating embryonic stem cells
Cells can secrete molecules that help each other’s replication. In cell cultures, chemical signals might diffuse only within a cell colony or between colonies. A chemical signal’s interaction length—how far ap...
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Open AccessSlowest possible replicative life at frigid temperatures for yeast
Determining whether life can progress arbitrarily slowly may reveal fundamental barriers to staying out of thermal equilibrium for living systems. By monitoring budding yeast’s slowed-down life at frigid tempe...
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Open AccessCorrection to: Predictive landscapes hidden beneath biological cellular automata
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Open AccessPredictive landscapes hidden beneath biological cellular automata
To celebrate Hans Frauenfelder’s achievements, we examine energy(-like) “landscapes” for complex living systems. Energy landscapes summarize all possible dynamics of some physical systems. Energy(-like) landsc...
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Yeasts collectively extend the limits of habitable temperatures by secreting glutathione
The conventional view is that high temperatures cause microorganisms to replicate slowly or die. In this view, microorganisms autonomously combat heat-induced damages. However, microorganisms co-exist with eac...
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Open AccessPresence of chest tubes does not affect the hemodynamic efficacy of standard cardiopulmonary resuscitation
During cardiopulmonary resuscitation (CPR), chest tubes can hinder increases in intrathoracic pressure by venting the pressure during chest compressions, thus reducing the blood flow generated by the thoracic ...
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Altruistic defence
A charitable deed by a few cells in a bacterial culture can help the rest of that population survive in the presence of antibiotics. This finding can aid further research into a major problem in public health.
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Growth landscape formed by perception and import of glucose in yeast
An important challenge in systems biology is to quantitatively describe microbial growth using a few measurable parameters that capture the essence of this complex phenomenon. Two key events at the cell membra...
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Article
Snowdrift game dynamics and facultative cheating in yeast
Yeast secrete invertase to break down sucrose into monosaccharides that they can metabolize. Gore et al. show that 99% of the monosaccharides diffuse away to where they can be used by other yeast cells, making th...
