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Article
Automatic diagnosis of myopic maculopathy using continuous severity ranking labels
Clinical lesions progress continuously but previous grading strategies are not fine-grained enough to model the continuously changing features of lesions. For lack of temporal sequential medical data to provid...
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Article
Advancing mid-infrared microdisk laser emission with Tm:YAG
Mid-infrared microcavity lasers have important applications in biosensing, mid-infrared spectroscopy, and environmental monitoring. However, the low output power of existing mid-infrared microcavity lasers hin...
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Article
Open AccessDiet quality from mid to late life and its association with physical frailty in late life in a cohort of Chinese adults
It is unclear if improving diet quality after midlife could reduce the risk of physical frailty at late life. We aimed to associate changes in diet quality after midlife with physical frailty at late life.
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Article
Adaptive enhancement of cataractous retinal images for contrast standardization
Cataract affects the quality of fundus images, especially the contrast, due to lens opacity. In this paper, we propose a scheme to enhance different cataractous retinal images to the same contrast as normal im...
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Article
Open AccessOptically pumped Milliwatt Whispering-Gallery microcavity laser
Whispering-gallery-mode microcavity lasers possess remarkable characteristics such as high Q factors and compact geometries, making them an essential element in the evolution of microlasers. However, solid-state ...
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Article
Precipitation Microphysical Characteristics of Typhoon Ewiniar (2018) before and after Its Final Landfall over Southern China
In this paper, the evolution of the microphysical characteristics in different regions (eyewall, inner core, and outer rainbands) and different quadrants [downshear left (DL), downshear right (DR), upshear lef...
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Article
Open AccessThe impact of Covid-19 in patients with chronic myeloid leukemia—a nationwide population-based study
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Article
Interaction between organic matter and tetracycline in river sediments in cold regions
In this study, the interaction between river sediments collected from cold regions and typical antibiotics was investigated. The results show that tetracycline addition to the sediment can promote the fluoresc...
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Article
Open AccessA new time-delayed periodic boundary condition for discrete element modelling of railway track under moving wheel loads
A new time-delayed periodic boundary condition (PBC) has been proposed for discrete element modelling (DEM) of periodic structures subject to moving loads such as railway track based on a box test which is nor...
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Article
Open AccessA hierarchical deep learning approach with transparency and interpretability based on small samples for glaucoma diagnosis
The application of deep learning algorithms for medical diagnosis in the real world faces challenges with transparency and interpretability. The labeling of large-scale samples leads to costly investment in de...
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Article
Open AccessDiscrete element modelling of two-layered ballast in a box test
It has been recently reported that ballast comprising differently graded layers helps to reduce track settlement. The main goal of this paper is to provide micro mechanical insight about how the differently la...
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Article
Science and Prediction of Heavy Rainfall over China: Research Progress since the Reform and Opening-Up of New China
This paper reviews the major progress on development of the science and prediction of heavy rainfall over China since the beginning of the reform and opening-up of new China (roughly between 1980 and 2019). Th...
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Article
Open AccessCombined lifestyle factors, incident cancer, and cancer mortality: a systematic review and meta-analysis of prospective cohort studies
Cancer poses a huge disease burden, which could be reduced by adopting healthy lifestyles mainly composed of healthy diet, body weight, physical activity, limited alcohol consumption, and avoidance of smoking....
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Article
Enhancement of blurry retinal image based on non-uniform contrast stretching and intensity transfer
Proper contrast and sufficient illuminance are important in clearly identifying the retinal structures, while the required quality cannot always be guaranteed due to major reasons like acquisition process and ...
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Article
An automatic evaluation method for retinal image registration based on similar vessel structure matching
Registration of retinal images is significant for clinical diagnosis. Numerous methods have been proposed to evaluate registration performance. The available evaluation methods can work well in normal image pa...
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Article
Combined lifestyle factors and risk of incident type 2 diabetes and prognosis among individuals with type 2 diabetes: a systematic review and meta-analysis of prospective cohort studies
A healthy lifestyle has been widely recommended for the prevention and management of type 2 diabetes. However, no systematic review has summarised the relationship between combined lifestyle factors (including...
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Article
N-doped carbon shell encapsulated PtZn intermetallic nanoparticles as highly efficient catalysts for fuel cells
The high cost and poor durability of Pt nanoparticles (NPs) have always been great challenges to the commercialization of proton exchange membrane fuel cells (PEMFCs). Pt-based intermetallic NPs with a highly ...
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Article
An Improved Full Convolutional Network Combined with Conditional Random Fields for Brain MR Image Segmentation Algorithm and its 3D Visualization Analysis
Existing brain region segmentation algorithms based on deep convolutional neural networks (CNN) are inefficient for object boundary segmentation. In order to enhance the segmentation accuracy of brain tissue, ...
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Article
Open AccessSmoking-induced risk of future cardiovascular disease is partly mediated by cadmium in tobacco: Malmö Diet and Cancer Cohort Study
Smoking is a strong risk factor for cardiovascular disease (CVD) and causes exposure to cadmium, which is a pro-atherosclerotic metal. Cadmium exposure has also been shown to increase the risk of CVD, even aft...
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Article
Open AccessExploring telomere length in mother–newborn pairs in relation to exposure to multiple toxic metals and potential modifying effects by nutritional factors
The uterine environment may influence telomere length at birth, which is essential for cellular function, aging, and disease susceptibility over the lifespan. However, little is known about the impact of toxic...
