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Open AccessCheckpoint kinase inhibitor AZD7762 enhance cisplatin-induced apoptosis in osteosarcoma cells
AZD7762 is a checkpoint kinase 1 (Chk 1) inhibitor, which has been reported to sensitize many tumor cells to DNA damage. However, whether AZD7762 could sensitize osteosarcoma cells to chemotherapy cisplatin ha...
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Open AccessEstrogen/ER in anti-tumor immunity regulation to tumor cell and tumor microenvironment
As the essential sexual hormone, estrogen and its receptor has been proved to participate in the regulation of autoimmunity diseases and anti-tumor immunity. The adjustment of tumor immunity is related to the ...