126 Result(s)

Article

Dental changes evaluated with a 3D computer-assisted model analysis after long-term tongue retaining device wear in OSA patients

Hui Chen, Alan A. Lowe, Arthur M. Strauss… in Sleep and Breathing (2009)

Article

Cytotoxicity and reversal of multidrug resistance by tryptanthrin-derived indoloquinazolines

To evaluate the effects and elucidate the mechanisms of a series of indoloquinazolines as novel anticancer agents.

Sung-tsai Yu, Ji-wang Chern, Tzer-ming Chen, Yi-fan Chiu… in Acta Pharmacologica Sinica (2010)

Article

Effects of diltiazem and propafenone on the inactivation and recovery kinetics of fKv1.4 channel currents expressed in Xenopus oocytes

To investigate the effects of diltiazem, an L-type calcium channel blocker, and propafenone, a sodium channel blocker, on the inactivation and recovery kinetics of fKv1.4, a potassium channel that generates th...

Dong Zhang, Shi-min Wang, Hui Chen, Xue-jun Jiang… in Acta Pharmacologica Sinica (2011)

Article

Oxidized low-density lipoprotein and β-glycerophosphate synergistically induce endothelial progenitor cell ossification

To investigate the ability of ox-LDL to induce ossification of endothelial progenitor cells (EPCs) in vitro and explored whether oxidative stress, especially hypoxia inducible factor-1α (HIF-1α) and reactive oxyg...

Li Liu, Zhi-zhong Liu, Hui Chen, Guo-jun Zhang, Yu-hua Kong… in Acta Pharmacologica Sinica (2011)

Article

An outbreak of coxsackievirus A6 hand, foot, and mouth disease associated with onychomadesis in Taiwan, 2010

In 2010, an outbreak of coxsackievirus A6 (CA6) hand, foot and mouth disease (HFMD) occurred in Taiwan and some patients presented with onychomadesis and desquamation following HFMD. Therefore, we performed an...

Sung-Hsi Wei, Yuan-Pin Huang, Ming-Chih Liu, Tsung-Pei Tsou… in BMC Infectious Diseases (2011)

Article

Plasma ghrelin levels are closely associated with severity and morphology of angiographically-detected coronary atherosclerosis in Chineses patients with diabetes mellitus

Low plasma ghrelin level was found to be associated with diabetes, and ghrelin was shown to inhibit pro-atherogenic changes in experimental models of atherosclerosis. The aim of this study was to investigate t...

Min Zhang, Wei-yi Fang, Fang Yuan, **n-kai Qu, Hua Liu… in Acta Pharmacologica Sinica (2012)

Article

The protective effects of ginsenoside Rg1 against hypertension target-organ damage in spontaneously hypertensive rats

Although a number of medicines are available for the management of hypertension, the organ damage induced by hypertension is not resolved. The aim of this study was to investigate the protection of ginsenoside...

Hui Chen, Jun Yin, Yanpin Deng, Min Yang… in BMC Complementary and Alternative Medicine (2012)

Article

Genetic diversity and drug resistance among newly diagnosed and antiretroviral treatment-naive HIV-infected individuals in western Yunnan: a hot area of viral recombination in China

The emergence of an HIV-1 epidemic in China was first recognized in Dehong, western Yunnan. Due to its geographic location, Dehong contributed greatly in bridging HIV-1 epidemics in Southeast Asia and China th...

Min Chen, Yanling Ma, Song Duan, Hui **ng, Shitang Yao… in BMC Infectious Diseases (2012)

Article

Comparison of the effects of antiarrhythmic drugs flecainide and verapamil on fKv1.4ΔN channel currents in Xenopus oocytes

To study the effects of Na⁺ channel blocker flecainide and L-type Ca²⁺ channel antagonist verapamil on the voltage-gated fKv1.4ΔN channel, an N-terminal-deleted mutant of the ferret Kv1.4 K⁺ channel.

Hui Chen, Dong Zhang, Sheng-** Chao, Jiang-hua Ren, Lin Xu… in Acta Pharmacologica Sinica (2013)

Article

The significance of LRPPRC overexpression in gastric cancer

LRPPRC is a multifunctional protein involved in mitochondrial gene expression and function, cell cycle progression, and tumorigenesis. We analyzed LRPPRC gene expression in 253 paired cases of gastric cancer a...

**aosa Li, Lifen Lv, Jianyong Zheng, **feng Zhou, Bing Liu, Hui Chen… in Medical Oncology (2013)

Article

Mechanism of curcumin resistance to human cytomegalovirus in HELF cells

We have previously shown that curcumin exhibited an outstanding anti-HCMV effect in vitro and in vivo. However, the underlying mechanism for the anti-HCMV effect remains unclear.

Yali Lv, Zhuoling An, Hui Chen, Zihui Wang… in BMC Complementary and Alternative Medicine (2014)

Article

Left ventricular filling pressure assessed by exercise TDI was correlated with early HFNEF in patients with non-obstructive hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM) patients are more susceptible to suffer from heart failure with normal ejection fraction (HFNEF). Therefore, it is critical to evaluate the relationship between left ventricul...

Guodong Ma, Ming Xu, Wei Gao, Zhao** Li, Weihong Li… in BMC Cardiovascular Disorders (2014)

Article

Danqi Pill regulates lipid metabolism disorder induced by myocardial ischemia through FATP-CPTI pathway

Danqi Pill (DQP), which contains Chinese herbs Salvia miltiorrhiza Bunge and Panax notoginseng, is widely used in the treatment of myocardial ischemia (MI) in China. Its regulatory effects on MI-associated lipid ...

Yong Wang, Chun Li, Qiyan Wang, Tianjiao Shi… in BMC Complementary and Alternative Medicine (2015)

Article

A protocol of histone modification-based mechanistic study of acupuncture in patients with stable angina pectoris

Angina pectoris (Angina) is a medical condition related to myocardial ischemia. Although acupuncture has been widely accepted as a clinical approach for angina, there is no sufficient evidence of its effective...

Ning Wang, Sheng-Feng Lu, Hui Chen… in BMC Complementary and Alternative Medicine (2015)

Article

Features of COPD patients by comparing CAT with mMRC: a retrospective, cross-sectional study

The group assignment of chronic obstructive pulmonary disease (COPD) may differ depending on whether the COPD assessment test (CAT) or modified Medical Research Council dyspnoea scale (mMRC) is used.

Wei-Chang Huang, Ming-Feng Wu, Hui-Chen Chen… in npj Primary Care Respiratory Medicine (2015)

Article

Target-controlled infusion of remifentanil with or without flurbiprofen axetil in sedation for extracorporeal shock wave lithotripsy of pancreatic stones: a prospective, open-label, randomized controlled trial

Extracorporeal shock wave lithotripsy (ESWL) is an effective therapeutic method used to treat patients with pancreatic stones. However, the anesthesia for this procedure has been underappreciated, with minimal...

Yu-Guang Yang, Liang-Hao Hu, Hui Chen, Bo Li, **ao-hua Fan… in BMC Anesthesiology (2015)

Article

Atorvastatin treatment improves effects of implanted mesenchymal stem cells: meta-analysis of animal models with acute myocardial infarction

Previous studies reported that Atorvastatin (ATOR) can improve the efficacy of Mesenchymal stem cells (MSCs) transplantation after acute myocardial infarction (AMI). However, the results of those studies were ...

Guo Dai, Qing Xu, Rong Luo, Jianfang Gao, Hui Chen… in BMC Cardiovascular Disorders (2015)

Article

Diabetic ketoacidosis presenting with atypical hemolytic uremic syndrome associated with a variant of complement factor B in an adult: a case report

Non-Shiga toxin-associated hemolytic uremic syndrome is known to be caused by dysregulation of the alternative complement pathway. Infections, drugs, pregnancy, bone marrow transplantation, malignancy, and aut...

Ziqiang Zhu, Hui Chen, Rupinder Gill, Jenchin Wang… in Journal of Medical Case Reports (2016)

Article

Clinico-pathological characteristics and outcomes of patients with biopsy-proven hypertensive nephrosclerosis: a retrospective cohort study

This study aimed to investigate renal outcomes and their predictors in biopsy-proven hypertensive nephrosclerosis (HN) patients and to compare clinico-pathological characteristics and prognoses between benign ...

Shaoshan Liang, Weibo Le, Dandan Liang, Hao Chen, Feng Xu, Hui** Chen… in BMC Nephrology (2016)

Article

Comparison of titanium elastic intramedullary nailing versus injection of bone marrow in treatment of simple bone cysts in children: a retrospective study

Simple bone cysts are common benign lytic bone lesions in children. The main goals of treatment for bone cysts are to prevent pathological fractures, support the healing process, and prevent recurrence. This r...

Wenchao Li, Ruijiang Xu, Minghua Du, Hui Chen in BMC Musculoskeletal Disorders (2016)