271 Result(s)
within
English
Science, Humanities and Social Sciences, multidisciplinary
Hui**g Chen
Article
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Fertility after intact ovary transplantation
Frozen banking of whole organs for transplantation is starting to look feasible.
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Open AccessA bioinformatic evaluation of potential allergenicity of 85 candidate genes in transgenic organisms
The potential of genetically modified organisms (GMOs) to increase allergenicity or predispositions to allergies has attracted much attention. An approach that will properly and holistically evaluate the aller...
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Open AccessPoly(benzyl ether) dendrons without conventional gelation motifs as a new kind of effective organogelators
Two poly(benzyl ether) dendrons, decorated in their periphery with nitrile groups, were divergently synthesized and fully characterized. Their gelation properties were studied by using scanning electron micros...
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Erratum: Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven cancers
Nature 501, 232–236 (2013); doi:10.1038/nature12441 In this Letter, the statement: ‘The authors declare competing financial interests: details accompany the full-text HTML version of the paper at www.nature.co...
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Open AccessBottom-Up Catalytic Approach towards Nitrogen-Enriched Mesoporous Carbons/Sulfur Composites for Superior Li-S Cathodes
We demonstrate a sustainable and efficient approach to produce high performance sulfur/carbon composite cathodes via a bottom-up catalytic approach. The selective oxidation of H2S by a nitrogen-enriched mesoporou...
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Open AccessThe optimal concentration of topical hydroxycamptothecin in preventing intraarticular scar adhesion
10-Hydroxycamptothecin could reduce intraarticular adhesion by inhibiting fibroblasts proliferation after knee surgery. However, the ideal concentration of hydroxycamptothecin have not been defined. This study...
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Open AccessGlucose-induced electrical activities and insulin secretion in pancreatic islet β-cells are modulated by CFTR
The cause of insulin insufficiency remains unknown in many diabetic cases. Up to 50% adult patients with cystic fibrosis (CF), a disease caused by mutations in the gene encoding the CF transmembrane conductanc...
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Open AccessMiR-198 represses tumor growth and metastasis in colorectal cancer by targeting fucosyl transferase 8
In this study we investigated the biological role and mechanism of miR-198 in colorectal carcinoma (CRC). MiR-198 expression was shown to exhibit a strongly negative correlation with lymph node invasion, dista...
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Open AccessWhole-cell biotransformation systems for reduction of prochiral carbonyl compounds to chiral alcohol in Escherichia coli
Lactobacillus brevis alcohol dehydrogenase (Lb-ADH) catalyzes reduction of prochiral carbonyl compounds to chiral alcohol and meanwhile consumes its cofactor NADH into NAD+, while the cofactor regeneration can be...
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Open AccessIsolated panniculitis with vasculitis of the male breast suspicious for malignancy on CT and ultrasound: a case report and literature review
We report a case of a 54-year-old male patient with a hard, painful nodule within his right breast which was misdiagnosed preoperatively as breast cancer.
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Open AccessThe first report of a Pelecaniformes defensin cluster: Characterization of β-defensin genes in the crested ibis based on BAC libraries
Defensins play a key role in the innate immunity of various organisms. Detailed genomic studies of the defensin cluster have only been reported in a limited number of birds. Herein, we present the first charac...
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Open AccessAssessing Telomere Length Using Surface Enhanced Raman Scattering
Telomere length can provide valuable insight into telomeres and telomerase related diseases, including cancer. Here, we present a brand-new optical telomere length measurement protocol using surface enhanced R...
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Open AccessControllable microwave three-wave mixing via a single three-level superconducting quantum circuit
Three-wave mixing in second-order nonlinear optical processes cannot occur in atomic systems due to the electric-dipole selection rules. In contrast, we demonstrate that second-order nonlinear processes can oc...
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Open AccessEvolutionary analysis of rubella viruses in mainland China during 2010–2012: endemic circulation of genotype 1E and introductions of genotype 2B
Rubella remains a significant burden in mainland China. In this report, 667 viruses collected in 24 of 31 provinces of mainland China during 2010–2012 were sequenced and analyzed, significantly extending previ...
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Open AccessCommunity structure of gut fungi during different developmental stages of the Chinese white pine beetle (Dendroctonus armandi)
The Chinese white pine beetle is arguably the most destructive forest insect in the Qinling Mountains in Northern China. Little is known about the structure of the fungal communities associated with Dendroctonus
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Open AccessEfficacy and biological safety of lopinavir/ritonavir based anti-retroviral therapy in HIV-1-infected patients: a meta-analysis of randomized controlled trials
Lopinavir/ritonavir (LPV/r) is the first ritonavir-boosted protease-inhibitor used in second-line anti-retroviral treatment (ART) in resource-limited regions. To evaluate the efficacy and safety outcomes of LP...
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Open AccessA Filifactor alocis-centered co-occurrence group associates with periodontitis across different oral habitats
Periodontitis is a highly prevalent polymicrobial disease worldwide, yet the synergistic pattern of the multiple oral pathogens involved is still poorly characterized. Here, saliva, supragingival and subgingiv...
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Open AccessAnchor-based classification and type-C inhibitors for tyrosine kinases
Tyrosine kinases regulate various biological processes and are drug targets for cancers. At present, the design of selective and anti-resistant inhibitors of kinases is an emergent task. Here, we inferred spec...
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Open AccessAntiviral Phosphorodiamidate Morpholino Oligomers are Protective against Chikungunya Virus Infection on Cell-based and Murine Models
Chikungunya virus (CHIKV) infection in human is associated with debilitating and persistent arthralgia and arthritis. Currently, there is no specific vaccine or effective antiviral available. Anti-CHIKV Phosph...
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Open AccessEnhanced Broadband Electromagnetic Absorption in Silicon Film with Photonic Crystal Surface and Random Gold Grooves Reflector
We show a hybrid structure consisting of Si film with photonic crystal surface and random triangular gold grooves reflector at the bottom, which is capable of realizing efficient, broad-band, wide-angle optica...
