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  1. Article

    Open Access

    Lineage tracing of mutant granulosa cells reveals in vivo protective mechanisms that prevent granulosa cell tumorigenesis

    Ovarian granulosa cell tumors (GCTs) originate from granulosa cells (GCs) and represent the most common sex cord-stromal tumor in humans. However, the developmental regulations and molecular mechanisms underly...

    Shudong Niu, Kaixin Cheng, Longzhong Jia, **g Liang, Lu Mu in Cell Death & Differentiation (2023)

  2. Article

    Open Access

    The efficacy and safety of temperature controlled dual-mode radiofrequency in women with vaginal laxity

    Vaginal laxity could negatively influence women’s sexual function. This study aimed to explore the efficacy and safety of temperature controlled dual-mode (monopolar and bipolar) radiofrequency (RF) in women w...

    Lixia FU, Senyang Long, Qin LI, Hainan XU, Ling Guo, Huarong Wang in BMC Women's Health (2023)

  3. Article

    Open Access

    HDAC3 maintains oocyte meiosis arrest by repressing amphiregulin expression before the LH surge

    It is known that granulosa cells (GCs) mediate gonadotropin-induced oocyte meiosis resumption by releasing EGF-like factors in mammals, however, the detailed molecular mechanisms remain unclear. Here, we demon...

    Huarong Wang, Han Cai, **ao Wang, Meiling Zhang, Bingying Liu in Nature Communications (2019)

  4. Article

    Open Access

    Natriuretic peptides improve the developmental competence of in vitro cultured porcine oocytes

    Natriuretic peptides (NPs), brain and C type NPs (BNP and CNP), were involved in the maintenance of porcine oocyte meiotic arrest. The present study investigated the effects of NPs on developmental competence ...

    Yanhao Zhang, Huarong Wang, Wei Liu, Ye Yang in Reproductive Biology and Endocrinology (2017)

  5. Article

    Open Access

    Estrogen receptors in granulosa cells govern meiotic resumption of pre-ovulatory oocytes in mammals

    In mammals, oocytes are arrested at the diplotene stage of meiosis I until the pre-ovulatory luteinizing hormone (LH) surge triggers meiotic resumption through the signals in follicular granulosa cells. In thi...

    Wei Liu, Qiliang **n, **ao Wang, Sheng Wang, Huarong Wang in Cell Death & Disease (2017)

  6. No Access

    Article

    Electrophysiological Correlates of Processing Own- and Other-Race Faces

    Most adults have more experience in identifying faces of their own race than in identifying faces from another race, and thus may be considered as own-race face experts. This effect was investigated by recordi...

    Yan Chen, Fada Pan, Huarong Wang, Shaobei **ao, Lun Zhao in Brain Topography (2013)