3 Result(s)

Article

CryoEM structures of anion exchanger 1 capture multiple states of inward- and outward-facing conformations

Anion exchanger 1 (AE1, band 3) is a major membrane protein of red blood cells and plays a key role in acid-base homeostasis, urine acidification, red blood cell shape regulation, and removal of carbon dioxide...

Hristina R. Zhekova, Jiansen Jiang, Weiguang Wang… in Communications Biology (2022)

Article

Publisher Correction: Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE

Weiguang Wang, Kirill Tsirulnikov, Hristina R. Zhekova… in Nature Communications (2021)

Article

Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE

SLC4 transporters play significant roles in pH regulation and cellular sodium transport. The previously solved structures of the outward facing (OF) conformation for AE1 (SLC4A1) and NBCe1 (SLC4A4) transporter...

Weiguang Wang, Kirill Tsirulnikov, Hristina R. Zhekova… in Nature Communications (2021)