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  1. Article

    Open Access

    25-hydroxycholesterol promotes proliferation and metastasis of lung adenocarcinoma cells by regulating ERβ/TNFRSF17 axis

    Lung adenocarcinoma is the main type of lung cancer in women. Our previous findings have evidenced that 25-hydroxycholesterol (25-HC) promotes migration and invasion of lung adenocarcinoma cells (LAC), during ...

    Mengting He, Wenbo Jiang, **ngkai Li, Hong** Liu, Hongsheng Ren in BMC Cancer (2024)

  2. Article

    Open Access

    Effects of bone marrow sparing radiotherapy on acute hematologic toxicity for patients with locoregionally advanced cervical cancer: a prospective phase II randomized controlled study

    To evaluate effects of bone marrow sparing (BMS) radiotherapy on decreasing the incidence of acute hematologic toxicity (HT) for locoregionally advanced cervical cancer (LACC) patients treated by pelvic irradi...

    Wen Li, Lan Ma, Fang Li, Kemin Li, Yang Zhang, Hongtao Ren, **ng Bao in Radiation Oncology (2024)

  3. Article

    Open Access

    Protective effect of synbiotic combination of Lactobacillus plantarum SC-5 and olive oil extract tyrosol in a murine model of ulcerative colitis

    Ulcerative colitisis (UC) classified as a form of inflammatory bowel diseases (IBD) characterized by chronic, nonspecific, and recurrent symptoms with a poor prognosis. Common clinical manifestations of UC inc...

    Fazheng Yu, Xueyu Hu, HongLin Ren, **aoxu Wang in Journal of Translational Medicine (2024)

  4. Article

    Open Access

    Identifying functional subtypes of IgA nephropathy based on three machine learning algorithms and WGCNA

    IgA nephropathy (IgAN) is one of the most common primary glomerulonephritis, which is a significant cause of renal failure. At present, the classification of IgAN is often limited to pathology, and its molecul...

    Hongbiao Ren, Wenhua Lv, Zhenwei Shang, Liangshuang Li, Qi Shen in BMC Medical Genomics (2024)

  5. Article

    Open Access

    Multi-omics sequencing revealed endostar combined with cisplatin treated non small cell lung cancer via anti-angiogenesis

    Endostar, an anti-angiogenic drug, has been approved for treating non-small cell lung cancer (NSCLC). At present, endostar combined with radiotherapy or chemotherapy has achieved ideal results in the treatment...

    Yufei Wang, Hong Ren in BMC Cancer (2024)

  6. No Access

    Article

    New Three-Dimensional Supramolecular Framework: Crystal Structure and Photocatalytic Property

    In this work, benzimidazole (Hbim) and Cu(II) ions ligands were chosen as building blocks to produce a novel Cu(II) compound (CP) based on {Cu4O}cluster, namely, [Cu4OCl6(Hbim)4]n·n(H2O)·2n(EtOH) (1). The investi...

    **g Li, Hongjiang Ren, Jiangtao Li in Journal of Fluorescence (2024)

  7. Article

    Open Access

    Identification and validation of eight lysosomes-related genes signatures and correlation with immune cell infiltration in lung adenocarcinoma

    Lung cancer is the leading cause of cancer-related death. Lysosomes are key degradative compartments that maintain protein homeostasis. In current study, we aimed to construct a lysosomes-related genes signatu...

    Dingli Song, Lili Zhao, Guang Zhao, Qian Hao, Jie Wu, Hong Ren in Cancer Cell International (2023)

  8. No Access

    Article

    A Missense Variant in AIFM1 Caused Mitochondrial Dysfunction and Intolerance to Riboflavin Deficiency

    AIFM1 is a mitochondrial flavoprotein involved in caspase-independent cell death and regulation of respiratory chain complex biogenesis. Mutations in the AIFM1 gene have been associated with multiple clinical phe...

    Ying Zhao, Yan Lin, Bin Wang, Fuchen Liu, Dandan Zhao, Wei Wang in NeuroMolecular Medicine (2023)

  9. No Access

    Article

    Synthesis and Fluorescent Characteristics Study of Two Novel Co(II) Complexes

    In this work, two novel mixed-ligand CPs that has a compositions of [Co2(µ-Hdppa)2(phen)2(H2O)2] (1) and {[Co(µ-Hdppa)(µ-4,4′-bipy)(H2O)]·H2O}n (2) is achieved through reaction of cobalt salts with the 5-(3,4-Dic...

    **g Li, Hongjiang Ren, Jiangtao Li, Liuchang Wang in Journal of Fluorescence (2023)

  10. No Access

    Article

    Potential Application Values of Two Multicoloured Coordination Compounds as Multicolor Luminescent Materials

    Two Co(II)-based coordination compounds, namely {[Co(apc)2]·H2O}n (1) and [Co(apc)2(H2O)2] (2), have been successfully prepared via reaction of a multifunctional ligand 2-aminopyrimidine-5-carboxylic acid (Hapc) ...

    **g Li, Hongjiang Ren, Jiangtao Li, Liuchang Wang in Journal of Fluorescence (2023)

  11. No Access

    Article

    Domain adaptive Sim-to-Real segmentation of oropharyngeal organs

    Video-assisted transoral tracheal intubation (TI) necessitates using an endoscope that helps the physician insert a tracheal tube into the glottis instead of the esophagus. The growing trend of robotic-assiste...

    Guankun Wang, Tian-Ao Ren, Jiewen Lai in Medical & Biological Engineering & Computi… (2023)

  12. No Access

    Article

    Transformer-based 3D U-Net for pulmonary vessel segmentation and artery-vein separation from CT images

    Transformer-based methods have led to the revolutionizing of multiple computer vision tasks. Inspired by this, we propose a transformer-based network with a channel-enhanced attention module to explore context...

    Yanan Wu, Shouliang Qi, Meihuan Wang in Medical & Biological Engineering & Computi… (2023)

  13. Article

    Open Access

    Function and autophagy of monocyte-derived dendritic cells is affected by hepatitis B virus infection

    The role of dendritic cells and the autophagy state of dendritic cells in the immune response of hepatitis B virus (HBV) infection was still controversial. In this study, we carefully examined the phenotype, f...

    Hua Xu, Juan Kang, Shan Zhong, Min Chen, Peng Hu, Hong Ren, Zhi Zhou in BMC Immunology (2023)

  14. No Access

    Article

    Application Values of Two Cu(II) Schiff Base Coordination Complexes on Blue Fluorescent Materials

    Two Schiff base binuclear Cu(II) compounds, [Cu2(L)2·(H2O)2]·2DMF (1) together with its coordination polymer (CP) [Cu2(L)2·(4,4′-bpy)2]n (2) (H2L is 4-hydroxy-3-((2-hydroxy-5-mercaptobenzylidene)amino)-2H-chromen...

    **g Li, Hongjiang Ren, Jiangtao Li in Journal of Fluorescence (2023)

  15. Article

    Open Access

    Correction: M6A associated TSUC7 inhibition contributed to Erlotinib resistance in lung adenocarcinoma through a notch signaling activation dependent way

    Kai Li, Zi-Yang Peng, Shan Gao in Journal of Experimental & Clinical Cancer … (2023)

  16. Article

    Open Access

    Enhancement of TKI sensitivity in lung adenocarcinoma through m6A-dependent translational repression of Wnt signaling by circ-FBXW7

    Tyrosine kinase inhibitors (TKIs) that specifically target mutational points in the EGFR gene have significantly reduced suffering and provided greater relief to patients with lung adenocarcinoma (LUAD). The t...

    Kai Li, Zi-Yang Peng, Rui Wang, **ang Li, Ning Du, Da-Peng Liu in Molecular Cancer (2023)

  17. No Access

    Article

    Flexible Needle Steering with Tethered and Untethered Actuation: Current States, Targeting Errors, Challenges and Opportunities

    Accurate needle targeting is critical for many clinical procedures, such as transcutaneous biopsy or radiofrequency ablation of tumors. However, targeting errors may arise, limiting the widespread adoption of ...

    Mingyue Lu, Yongde Zhang, Chwee Ming Lim, Hongliang Ren in Annals of Biomedical Engineering (2023)

  18. Article

    The safety and immunogenicity of inactivated COVID-19 vaccine in old pulmonary tuberculosis patients

    The immunogenicity and safety of vaccines against coronavirus disease 2019 (COVID-19) remain unknown in patients with a history of pulmonary tuberculosis (OPTB). Therefore, the safety and effectiveness of inac...

    Lei Yang, Feng **ang, Dian Wang, Qiao Guo in European Journal of Clinical Microbiology … (2023)

  19. Article

    Open Access

    Impaired antibody responses were observed in patients with type 2 diabetes mellitus after receiving the inactivated COVID-19 vaccines

    Patients with type 2 diabetes mellitus (T2DM) have been reported to be more susceptible to 2019 novel coronavirus (2019-nCoV) and more likely to develop severe pneumonia. However, the safety and immunological ...

    Feng **ang, Boyu Long, Jiaoxia He, Feifei Cheng, Si**g Zhang, Qing Liu in Virology Journal (2023)

  20. Article

    Open Access

    Mutation in XPO5 causes adult-onset autosomal dominant familial focal segmental glomerulosclerosis

    Focal and segmental glomerulosclerosis (FSGS) is a histological pathology that characterizes a wide spectrum of diseases. Many genes associated with FSGS have been studied previously, but there are still some ...

    Hafiz Muhammad Jafar Hussain, Yikai Cai, Qinjie Weng, Jun Tong in Human Genomics (2022)

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