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  1. Article

    Open Access

    Association between oligo-residual disease and patterns of failure during EGFR-TKI treatment in EGFR-mutated non-small cell lung cancer: a retrospective study

    Local ablative therapy (LAT) may be beneficial for patients with epidermal growth factor receptor (EGFR) mutated non-small cell lung cancer (NSCLC) with oligo-residual disease after treatment with EGFR tyrosine k...

    Taichi Miyawaki, Hirotsugu Kenmotsu, Hiroaki Kodama, Naoya Nishioka in BMC Cancer (2021)

  2. Article

    Open Access

    Phase II study of multidisciplinary therapy combined with pembrolizumab for patients with synchronous oligometastatic non-small cell lung cancer TRAP OLIGO study (WJOG11118L)

    Synchronous oligometastatic non-small cell lung cancer (NSCLC) is generally characterised by the limited number of metastases at the time of diagnosis. Several clinical trials have shown that local ablative th...

    Taichi Miyawaki, Hirotsugu Kenmotsu, Hideyuki Harada, Yasuhisa Ohde in BMC Cancer (2021)

  3. Article

    Open Access

    Retrospective analysis of salvage surgery for local progression of brain metastasis previously treated with stereotactic irradiation: diagnostic contribution, functional outcome, and prognostic factors

    Stereotactic irradiation (STI) is a primary treatment for patients with newly diagnosed brain metastases. Some of these patients experience local progression, which is difficult to differentiate from radiation...

    Koichi Mitsuya, Yoko Nakasu, Nakamasa Hayashi, Shoichi Deguchi, Takuma Oishi in BMC Cancer (2020)

  4. Article

    Open Access

    A randomised phase II trial of S-1 plus cisplatin versus vinorelbine plus cisplatin with concurrent thoracic radiotherapy for unresectable, locally advanced non-small cell lung cancer: WJOG5008L

    Cisplatin-based chemoradiotherapy is the standard treatment for unresectable, locally advanced non-small-cell lung cancer (NSCLC). This trial evaluated two experimental regimens that combine chemotherapy with ...

    Tomonari Sasaki, Takashi Seto, Takeharu Yamanaka in British Journal of Cancer (2018)

  5. Article

    Open Access

    Expansive hematoma in delayed cerebral radiation necrosis in patients treated with T-DM1: a report of two cases

    Multiple new targeted agents have been developed for patients with human epidermal growth factor receptor type 2 (HER2) – positive breast cancer. Patients with HER2– positive breast cancer will develop brain m...

    Koichi Mitsuya, Junichiro Watanabe, Yoko Nakasu, Nakamasa Hayashi in BMC Cancer (2016)

  6. Article

    Open Access

    Prognostic significance of diabetes mellitus in locally advanced non-small cell lung cancer

    To investigate the prognostic significance of patient characteristics and clinical laboratory test results in locally advanced non-small cell lung cancer (NSCLC), and in particular the impact of diabetes melli...

    Hisao Imai, Kyoichi Kaira, Keita Mori, Akira Ono, Hiroaki Akamatsu in BMC Cancer (2015)

  7. Article

    Open Access

    Progression-free survival at 2 years is a reliable surrogate marker for the 5-year survival rate in patients with locally advanced non-small cell lung cancer treated with chemoradiotherapy

    In locally advanced Non-Small-Cell Lung Cancer (LA-NSCLC) patients treated with chemoradiotherapy (CRT), optimal surrogate endpoint for cure has not been fully investigated.

    Hiroaki Akamatsu, Keita Mori, Tateaki Naito, Hisao Imai, Akira Ono in BMC Cancer (2014)