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  1. No Access

    Article

    Endoscopic debulking canalization for optic pathway glioma with obstructive hydrocephalus

    Optic pathway gliomas (OPGs) are benign tumors that can stop growing or even shrink. In recent years, surgical resection has not been considered the first-line treatment because of its high risk of complicatio...

    Kazuhito Takeuchi, Fumiharu Ohka, Yuichi Nagata, Eiji Ito in Child's Nervous System (2023)

  2. Article

    Open Access

    Correction: Feasibility of linac-based fractionated stereotactic radiotherapy and stereotactic radiosurgery for patients with up to ten brain metastases

    Masanori Hirata, Kazuaki Yasui, Naofumi Oota, Hirofumi Ogawa in Radiation Oncology (2023)

  3. No Access

    Article

    Incidence of and risk factors for non-hematologic toxicity with combined radiotherapy and CDK4/6 inhibitors in metastatic breast cancer using dose-volume parameters analysis: a multicenter cohort study

    There is a lack of data on combined radiotherapy (RT) and cyclin-dependent kinase 4 and 6 inhibitor (CDK4/6i) risk factors and toxicity. This study aimed to assess the incidence of and risk factors for non-hem...

    Terufumi Kawamoto, Naoto Shikama, Nobuki Imano, Hikaru Kubota in Breast Cancer (2023)

  4. No Access

    Article

    The importance of preserving the superior hypophyseal artery infundibular branch in craniopharyngioma surgery

    Postoperative pituitary dysfunction, a critical problem in the treatment of craniopharyngiomas, can occur even when the pituitary stalk is preserved. We hypothesized that compromise of the primary superior hyp...

    Hiroo Sasaki, Kazuhito Takeuchi, Yuichi Nagata, Kuniaki Tanahashi in Acta Neurochirurgica (2023)

  5. Article

    Open Access

    Osteosclerotic change as a therapeutic response to gefitinib in symptomatic non-small cell lung cancer bone metastasis

    Despite improvement in the overall survival of patients with non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR) mutation, the effects of EGFR tyrosine kinase inhibitor (EGFR-T...

    Michihito Miyagi, Hirohisa Katagiri, Hideki Murata, Junji Wasa in BMC Pulmonary Medicine (2022)

  6. Article

    Open Access

    Feasibility of linac-based fractionated stereotactic radiotherapy and stereotactic radiosurgery for patients with up to ten brain metastases

    Linac-based fractionated stereotactic radiotherapy (fSRT) and stereotactic radiosurgery (SRS) are increasingly being used to manage patients with multiple metastases. This retrospective cohort study aimed to c...

    Masanori Hirata, Kazuaki Yasui, Naofumi Oota, Hirofumi Ogawa in Radiation Oncology (2022)

  7. No Access

    Article

    Efficacy and safety of the endoscopic “wet-field” technique for removal of supratentorial cavernous malformations

    Cerebral cavernous malformations (CMs) presenting with focal neurological symptoms or mass effects require surgical removal. In recent years, cylindrical retractors have been widely utilized for the removal of...

    Kazuhito Takeuchi, Yuichi Nagata, Kuniaki Tanahashi, Yoshio Araki in Acta Neurochirurgica (2022)

  8. No Access

    Article

    Recent Characteristics of Fog Water Chemistry at Mt. Tateyama, Central Japan: Recovery from High Sulfate and Acidity

    Measurements of chemical compositions in the fog water at Murododaira (36.6°N, 137.6°E, altitude 2450 m), Mt. Tateyama, on the Sea of Japan side of central Japan, were performed mainly in autumn, and the chara...

    Koichi Watanabe, Jiujiu Ji, Hideyuki Harada, Yutaro Sunada in Water, Air, & Soil Pollution (2022)

  9. No Access

    Article

    Multi-institutional feasibility study of intensity-modulated radiotherapy with chemotherapy for locally advanced non-small cell lung cancer

    This multi-institutional clinical trial evaluated the feasibility of intensity-modulated radiotherapy (IMRT) for patients with locally advanced non-small cell lung cancer (NSCLC).

    Hideyuki Harada, Shota Omori, Keita Mori in International Journal of Clinical Oncology (2022)

  10. Article

    Correction to: Prognostic impact of pneumonitis after durvalumab therapy in patients with locally advanced non‑small cell lung cancer

    Ari Nishimura, Akira Ono, Kazushige Wakuda, Takanori Kawabata in Investigational New Drugs (2022)

  11. No Access

    Article

    Long-term survival data of patients with limited disease small cell lung cancer: a retrospective analysis

    Introduction: In patients with limited disease small cell lung cancer (LD-SCLC) treated with concurrent chemoradiotherapy (CCRT), long-term survival data have not been fully evaluated. Moreover, the association b...

    Kosei Doshita, Hirotsugu Kenmotsu, Shota Omori, Yuya Tabuchi in Investigational New Drugs (2022)

  12. No Access

    Article

    A novel endoscopic ventriculocisternostomy and stenting technique with a transparent acryl puncture needle for a trapped temporal horn: a technical report and literature review

    Trapped temporal horn is a rare type of noncommunicating focal hydrocephalus, and no standard treatment has been established yet for trapped temporal horn. Recent studies have shown the efficacy of endoscopic ...

    Taiki Yamamoto, Kazuhito Takeuchi, Yuichi Nagata, Akihiro Mizuno in Neurosurgical Review (2022)

  13. Article

    Open Access

    Prognostic impact of pneumonitis after durvalumab therapy in patients with locally advanced non-small cell lung cancer

    Background. Prognostic data on Japanese patients receiving durvalumab after chemoradiotherapy (CRT) for locally advanced non-small cell lung cancer (LA-NSCLC) are insufficient. Whether pneumonitis has prognostic ...

    Ari Nishimura, Akira Ono, Kazushige Wakuda, Takanori Kawabata in Investigational New Drugs (2022)

  14. Article

    Open Access

    Neoadjuvant fractionated stereotactic radiotherapy followed by piecemeal resection of brain metastasis: a case series of 20 patients

    The safety and effectiveness of neoadjuvant fractionated stereotactic radiotherapy (FSRT) before piecemeal resection of brain metastasis (BM) remains unknown.

    Shoichi Deguchi, Koichi Mitsuya in International Journal of Clinical Oncology (2022)

  15. No Access

    Article

    Phase I study of weekly nab-paclitaxel plus carboplatin and concurrent thoracic radiotherapy in elderly patients with unresectable locally advanced non-small cell lung cancer

    Few clinical studies have been designed for elderly patients with locally advanced non-small cell lung cancer (NSCLC). We conducted a phase I study to evaluate the tolerability of carboplatin/nab-paclitaxel an...

    Shota Omori, Hideyuki Harada, Keita Mori, Yasushi Hisamatsu in Investigational New Drugs (2022)

  16. No Access

    Article

    Impact of weight loss on treatment with PD-1/PD-L1 inhibitors plus chemotherapy in advanced non-small-cell lung cancer

    Programmed cell death-1 (PD-1)/programmed death-ligand 1 (PD-L1) inhibitors plus chemotherapy have become the standard first line of treatment in patients with advanced non-small-cell lung cancer (NSCLC). Howe...

    Taichi Miyawaki, Tateaki Naito, Michitoshi Yabe in Supportive Care in Cancer (2022)

  17. No Access

    Article

    Rechallenge with previously administered epidermal growth factor receptor-tyrosine kinase inhibitors in EGFR-mutated non-small cell lung cancer with leptomeningeal metastasis

    Objectives In EGFR-mutated non-small cell lung cancer (NSCLC) patients, approximately 80–90% of leptomeningeal metastasis (LM) develops after failed initial treatment with epidermal growth factor receptor (EGFR) ...

    Taichi Miyawaki, Hirotsugu Kenmotsu, Michitoshi Yabe in Investigational New Drugs (2021)

  18. Article

    Open Access

    Association between oligo-residual disease and patterns of failure during EGFR-TKI treatment in EGFR-mutated non-small cell lung cancer: a retrospective study

    Local ablative therapy (LAT) may be beneficial for patients with epidermal growth factor receptor (EGFR) mutated non-small cell lung cancer (NSCLC) with oligo-residual disease after treatment with EGFR tyrosine k...

    Taichi Miyawaki, Hirotsugu Kenmotsu, Hiroaki Kodama, Naoya Nishioka in BMC Cancer (2021)

  19. Article

    Open Access

    Phase II study of multidisciplinary therapy combined with pembrolizumab for patients with synchronous oligometastatic non-small cell lung cancer TRAP OLIGO study (WJOG11118L)

    Synchronous oligometastatic non-small cell lung cancer (NSCLC) is generally characterised by the limited number of metastases at the time of diagnosis. Several clinical trials have shown that local ablative th...

    Taichi Miyawaki, Hirotsugu Kenmotsu, Hideyuki Harada, Yasuhisa Ohde in BMC Cancer (2021)

  20. No Access

    Article

    Leptomeningeal Metastasis in ER + HER2- Advanced Breast Cancer Patients: A Review of the Cases in a Single Institute Over a 15-year Period

    While leptomeningeal metastasis (LM) from estrogen receptor-positive, HER2-negative advanced breast cancer (ER + HER2-ABC) has a poor prognosis, the details of ER + HER2-LM are unclear. We therefore retrospect...

    Junichiro Watanabe, Koichi Mitsuya, Shogo Nakamoto in Breast Cancer Research and Treatment (2021)

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