-
Article
The resilience framework as a strategy to combat stress-related disorders
Consistent failure over the past few decades to reduce the high prevalence of stress-related disorders has motivated a search for alternative research strategies. Resilience refers to the phenomenon of many pe...
-
Article
Identification of neurobehavioural symptom groups based on shared brain mechanisms
Most psychopathological disorders develop in adolescence. The biological basis for this development is poorly understood. To enhance diagnostic characterization and develop improved targeted interventions, it ...
-
Article
Dissociating neural learning signals in human sign- and goal-trackers
Individuals differ in how they learn from experience. In Pavlovian conditioning models, where cues predict reinforcer delivery at a different goal location, some animals—called sign-trackers—come to approach t...
-
Article
Neurobehavioural characterisation and stratification of reinforcement-related behaviour
Reinforcement-related cognitive processes, such as reward processing, inhibitory control and social–emotional regulation are critical components of externalising and internalising behaviours. It is unclear to ...
-
Article
Global urbanicity is associated with brain and behaviour in young people
Urbanicity is a growing environmental challenge for mental health. Here, we investigate correlations of urbanicity with brain structure and function, neuropsychology and mental illness symptoms in young people...
-
Article
Genetic architectures of cerebral ventricles and their overlap with neuropsychiatric traits
The cerebral ventricles are recognized as windows into brain development and disease, yet their genetic architectures, underlying neural mechanisms and utility in maintaining brain health remain elusive. Here ...
-
Article
The genetic architecture of the human hypothalamus and its involvement in neuropsychiatric behaviours and disorders
Despite its crucial role in the regulation of vital metabolic and neurological functions, the genetic architecture of the hypothalamus remains unknown. Here we conducted multivariate genome-wide association st...