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  1. Article

    CRF-Amplified Neuronal TLR4/MCP-1 Signaling Regulates Alcohol Self-Administration

    Alcohol dependence is a complex disorder that initiates with episodes of excessive alcohol drinking known as binge drinking. It has a 50–60% risk contribution from inherited susceptibility genes; however, thei...

    Harry L June, Juan Liu, Kaitlin T Warnock, Kimberly A Bell in Neuropsychopharmacology (2015)

  2. Article

    Central Opioid Receptors Differentially Regulate the Nalmefene-Induced Suppression of Ethanol- and Saccharin-Reinforced Behaviors in Alcohol-Preferring (P) Rats

    The exact opioid-sensitive receptors participating in EtOH-seeking behaviors remains unclear. Previous studies have reported higher densities of μ-opioid receptor binding in the nucleus accumbens (NACC) of P rela...

    Harry L June, Rancia Cummings, William J A Eiler II in Neuropsychopharmacology (2004)

  3. Article

    GABAA and Opioid Receptors of the Central Nucleus of the Amygdala Selectively Regulate Ethanol-Maintained Behaviors

    The present study tested the hypothesis that GABAA and opioid receptors within the central nucleus of the amygdala (CeA) regulate ethanol (EtOH), but not sucrose-maintained responding. To accomplish this, βCCt, a...

    Katrina L Foster, Peter F McKay, Regat Seyoum, Dana Milbourne in Neuropsychopharmacology (2004)

  4. Article

    The Reinforcing Properties of Alcohol are Mediated by GABAA1 Receptors in the Ventral Pallidum

    It has been hypothesized that alcohol addiction is mediated, at least in part, by specific γ-aminobutyric acidA (GABAA) receptors within the ventral pallidum (VP). Among the potential GABAA receptor isoforms regu...

    Harry L June, Katrina L Foster, Peter F McKay, Regat Seyoum in Neuropsychopharmacology (2003)