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    Article

    The X-linked inhibitor of apoptosis protein (XIAP) is involved in melanoma invasion by regulating cell migration and survival

    The X-linked inhibitor of apoptosis (XIAP) is a potent cellular inhibitor of apoptosis, based on its unique capability to bind and to inhibit caspases. However, XIAP is also involved in a number of additional ...

    Ouissam Ayachi, Meltem Barlin, Pia Nora Broxtermann, Hamid Kashkar in Cellular Oncology (2019)

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    Open Access

    Elevated X-linked inhibitor of apoptosis protein (XIAP) expression uncovers detrimental prognosis in subgroups of neoadjuvant treated and T-cell rich esophageal adenocarcinoma

    Molecular markers predicting survival in esophageal adenocarcinoma (EAC) are rare. Specifically, in favorable oncologic situations, e.g. nodal negativity or major neoadjuvant therapy response, there is a lack ...

    Lars M. Schiffmann, Heike Göbel, Heike Löser, Fabian Schorn in BMC Cancer (2019)

  3. Article

    Open Access

    Tumour-infiltrating neutrophils counteract anti-VEGF therapy in metastatic colorectal cancer

    Immune infiltration is implicated in the development of acquired resistance to anti-angiogenic cancer therapy. We therefore investigated the correlation between neutrophil infiltration in metastasis of colorec...

    Lars Mortimer Schiffmann, Melanie Fritsch, Florian Gebauer in British Journal of Cancer (2019)