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    Article

    Flow cytometric immunobead assay for the detection of BCR–ABL fusion proteins in leukemia patients

    BCR–ABL fusion proteins show increased signaling through their ABL tyrosine kinase domain, which can be blocked by specific inhibitors, thereby providing effective treatment. This makes detection of BCRABL aberr...

    F Weerkamp, E Dekking, Y Y Ng, V H J van der Velden, H Wai, S Böttcher in Leukemia (2009)

  2. Article

    Open Access

    Flow cytometric immunobead assay for fast and easy detection of PML–RARA fusion proteins for the diagnosis of acute promyelocytic leukemia

    The PML–RARA fusion protein is found in approximately 97% of patients with acute promyelocytic leukemia (APL). APL can be associated with life-threatening bleeding complications when undiagnosed and not treate...

    E H A Dekking, V H J van der Velden, R Varro, H Wai, S Böttcher, M Kneba in Leukemia (2012)