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Molecular analysis of an asbestos-exposed Belgian family with a high prevalence of mesothelioma

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  1. Article

    Open Access

    CRISPR/Cas9-edited ROS1 + non-small cell lung cancer cell lines highlight differential drug sensitivity in 2D vs 3D cultures while reflecting established resistance profiles

    The study of resistance-causing mutations in oncogene-driven tumors is fundamental to guide clinical decisions. Several point mutations affecting the ROS1 kinase domain have been identified in the clinical set...

    Marc Terrones, Christophe Deben… in Journal of Translational Medicine (2024)

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  2. Article

    Open Access

    Long-term acquired everolimus resistance in pancreatic neuroendocrine tumours can be overcome with novel PI3K-AKT-mTOR inhibitors

    The mTOR-inhibitor everolimus improves progression-free survival in advanced pancreatic neuroendocrine tumours (PNETs). However, adaptive resistance to mTOR inhibition is described.

    Timon Vandamme, Matthias Beyens, Ken Op de Beeck, Fadime Dogan… in British Journal of Cancer (2016)

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  3. Article

    Deafness linked to DFNA2: one locus but how many genes?

    Peter Van Hauwe, Paul J. Coucke, Frank Declau, Henricus Kunst… in Nature Genetics (1999)

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