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  1. Article

    Open Access

    Long-term acquired everolimus resistance in pancreatic neuroendocrine tumours can be overcome with novel PI3K-AKT-mTOR inhibitors

    The mTOR-inhibitor everolimus improves progression-free survival in advanced pancreatic neuroendocrine tumours (PNETs). However, adaptive resistance to mTOR inhibition is described.

    Timon Vandamme, Matthias Beyens, Ken Op de Beeck, Fadime Dogan in British Journal of Cancer (2016)