97 Result(s)
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Open AccessUnique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing
Leptospirosis is a widely spread disease of global concern. Infection causes flu-like episodes with frequent severe renal and hepatic damage, such as haemorrhage and jaundice. In more severe cases, massive pul...
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Open AccessUltrafast universal quantum control of a quantum-dot charge qubit using Landau–Zener–Stückelberg interference
A basic requirement for quantum information processing is the ability to universally control the state of a single qubit on timescales much shorter than the coherence time. Although ultrafast optical control o...
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Open AccessGenome of the Chinese tree shrew
Chinese tree shrews (Tupaia belangeri chinensis) possess many features valuable in animals used as experimental models in biomedical research. Currently, there are numerous attempts to employ tree shrews as model...
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Open AccessTopological insulator bismuth selenide as a theranostic platform for simultaneous cancer imaging and therapy
Employing theranostic nanoparticles, which combine both therapeutic and diagnostic capabilities in one dose, has promise to propel the biomedical field toward personalized medicine. Here we investigate the the...
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Open AccessTuning inter-dot tunnel coupling of an etched graphene double quantum dot by adjacent metal gates
Graphene double quantum dots (DQDs) open to use charge or spin degrees of freedom for storing and manipulating quantum information in this new electronic material. However, impurities and edge disorders in etc...
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Correction: Corrigendum: Ultrafast universal quantum control of a quantum-dot charge qubit using Landau–Zener–Stückelberg interference
Nature Communications 4: Article number: 1401 (2013); Published 29 January 2013; Updated 13 November 2013 In the original version of this Article, we claimed electrical control of a quantum-dot charge qubit on...
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Open AccessTRAF1 is a critical regulator of cerebral ischaemia–reperfusion injury and neuronal death
Stroke is a leading global cause of mortality and disability. Less than 5% of patients are able to receive tissue plasminogen activator thrombolysis within the necessary timeframe. Focusing on the process of n...
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Open AccessLong-term intensive management increased carbon occluded in phytolith (PhytOC) in bamboo forest soils
Carbon (C) occluded in phytolith (PhytOC) is highly stable at millennium scale and its accumulation in soils can help increase long-term C sequestration. Here, we report that soil PhytOC storage significantly ...
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Open AccessIRF8 suppresses pathological cardiac remodelling by inhibiting calcineurin signalling
Interferon regulatory factor 8 (IRF8) is known to affect the innate immune response, for example, by regulating the differentiation and function of immune cells. However, whether IRF8 can influence cardiac hyp...
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Open Access2′-Epi-uscharin from the Latex of Calotropis gigantea with HIF-1 Inhibitory Activity
Two stereoisomeric cardenolides, uscharin (1) and a new compound, 2′-epi-uscharin (2), were isolated from the latex of Calotropis gigantea (Asclepiadaceae). Their structures were fully elucidated based on their s...
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Open AccessNovel Na2Mo4O13/α-MoO3 hybrid material as highly efficient CWAO catalyst for dye degradation at ambient conditions
We report a novel hybrid material Na2Mo4O13/α-MoO3 as highly efficient catalytic wet air oxidation (CWAO) catalyst, which showed the highest ever activity at room temperature and atmosphere pressure for the degra...
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Open AccessThe complex jujube genome provides insights into fruit tree biology
The jujube (Ziziphus jujuba Mill.), a member of family Rhamnaceae, is a major dry fruit and a traditional herbal medicine for more than one billion people. Here we present a high-quality sequence for the complex ...
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Open AccessIntracellular CD24 disrupts the ARF–NPM interaction and enables mutational and viral oncogene-mediated p53 inactivation
CD24 is overexpressed in nearly 70% human cancers, whereas TP53 is the most frequently mutated tumour-suppressor gene that functions in a context-dependent manner. Here we show that both targeted mutation and sho...
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Open AccessSuspending Effect on Low-Frequency Charge Noise in Graphene Quantum Dot
Charge noise is critical in the performance of gate-controlled quantum dots (QDs). Such information is not yet available for QDs made out of the new material graphene, where both substrate and edge states are ...
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Open AccessGenetic polymorphism analyses of 30 InDels in Chinese **be ethnic group and its population genetic differentiations with other groups
In the present study, we obtained population genetic data and forensic parameters of 30 InDel loci in Chinese **be ethnic group from northwestern China and studied the genetic relationships between the studied...
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Open Access3, 4-dihydroxyl-phenyl lactic acid restores NADH dehydrogenase 1 α subunit 10 to ameliorate cardiac reperfusion injury
The present study aimed to detect the role of 3, 4-dihydroxyl-phenyl lactic acid (DLA) during ischemia/reperfusion (I/R) induced myocardial injury with emphasis on the underlying mechanism of DLA antioxidant. ...
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Open AccessDe novo Assembly and Characterization of the Testis Transcriptome and Development of EST-SSR Markers in the Cockroach Periplaneta americana
The cockroach Periplaneta americana is a notorious pest and threat to health worldwide, with a high reproductive ability. However, a limited amount of data is available on the developmental stage-specific transcr...
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Open AccessMannan-modified adenovirus targeting TERT and VEGFR-2: A universal tumour vaccine
Antigen-presenting cells including dendritic cells (DCs) express mannan receptors (MR) on their surface, which can be exploited in cancer therapy by designing immune-stimulatory viruses coated with mannan-modi...
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Open AccessConditional rotation of two strongly coupled semiconductor charge qubits
Universal multiple-qubit gates can be implemented by a set of universal single-qubit gates and any one kind of entangling two-qubit gate, such as a controlled-NOT gate. For semiconductor quantum dot qubits, tw...
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Open AccessSilencing a sugar transporter gene reduces growth and fecundity in the brown planthopper, Nilaparvata lugens (Stål) (Hemiptera: Delphacidae)
The brown planthopper (BPH), Nilaparvata lugens, sugar transporter gene 6 (Nlst6) is a facilitative glucose/fructose transporter (often called a passive carrier) expressed in midgut that mediates sugar transport ...
