1,253 Result(s)
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Article
Laser additive manufacturing of titanium alloys: process, materials and post-processing
Laser additive manufacturing (LAM) of titanium (Ti) alloys has emerged as a transformative technology with vast potential across multiple industries. To recap the state of the art, Ti alloys processed by two e...
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Article
The centrosymmetric to non-centrosymmetric transformation induced by alkaline-earth cations producing infrared nonlinear optical AeMn6Ga6S16 (Ae = Ca, Sr)
Non-centrosymmetric (NCS) structure is an indispensable prerequisite for second-order nonlinear optical (NLO) material. Currently, the mainstream approach for designing new NCS structures still relies on chemi...
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A small molecule compound targeting hemagglutinin inhibits influenza A virus and exhibits broad-spectrum antiviral activity
Influenza A virus (IAV) is a widespread pathogen that poses a significant threat to human health, causing pandemics with high mortality and pathogenicity. Given the emergence of increasingly drug-resistant str...
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Article
Ha-gnn: a novel graph neural network based on hyperbolic attention
Graph neural networks (GNNs) are powerful tools for data mining on graph-structured data in various domains, such as social science, finance, and biology. However, most existing GNNs operate in Euclidean space...
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Article
Open AccessDirect radical functionalization of native sugars
Naturally occurring (native) sugars and carbohydrates contain numerous hydroxyl groups of similar reactivity1,2. Chemists, therefore, rely typically on laborious, multi-step protecting-group strategies3 to conver...
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Advances in catalysts and reaction systems for electro/photocatalytic ammonia production
Ammonia is a vital component in the fertilizer and chemical industries, as well as serving as a significant carrier of renewable hydrogen energy. Compared with the industry’s principal technique, the Haber-Bos...
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Polyoxometalate as the assembly material to self-assembled Ni(OH)2 nanosheets with electrocatalytic performance
Develo** non-noble metal-based electrocatalyst with high catalytic activity is essential for advancing hydrogen energy technologies. This study introduces a hydrothermal method for synthesizing order Ni(OH)2 na...
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Open AccessDistinct characteristics of the gut virome in patients with osteoarthritis and gouty arthritis
The gut microbiota and its metabolites play crucial roles in pathogenesis of arthritis, highlighting gut microbiota as a promising avenue for modulating autoimmunity. However, the characterization of the gut v...
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Open AccessDe novo design of a nanoregulator for the dynamic restoration of ovarian tissue in cryopreservation and transplantation
The cryopreservation and transplantation of ovarian tissue underscore its paramount importance in safeguarding reproductive capacity and ameliorating reproductive disorders. However, challenges persist in ovar...
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Open AccessTREM2 deficiency aggravates renal injury by promoting macrophage apoptosis and polarization via the JAK-STAT pathway in mice
The triggering receptor expressed on myeloid cells 2 (TREM2) is an immune receptor that affects cellular phenotypes by modulating phagocytosis and metabolism, promoting cell survival, and counteracting inflamm...
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Open AccessRevealing brain cell-stratified causality through dissecting causal variants according to their cell-type-specific effects on gene expression
The human brain has been implicated in the pathogenesis of several complex diseases. Taking advantage of single-cell techniques, genome-wide association studies (GWAS) have taken it a step further and revealed...
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Pristine UiO-67 nanoparticles for zinc dendrite inhibition
One of the main reasons that limit the application of aqueous zinc ion batteries (ZIBs) is the growth of zinc dendrites. In this paper, three different sizes of UiO-67 were synthesized, named B-10, B-15 and B-...
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Open AccessStructural basis for recognition of 26RFa by the pyroglutamylated RFamide peptide receptor
The neuropeptide 26RFa, a member of the RF-amide peptide family, activates the pyroglutamylated RF-amide peptide receptor (QRFPR), a class A GPCR. The 26RFa/QRFPR system plays critical roles in energy homeosta...
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Article
Effect of distance between heat sources on droplet transfer behavior and weld formation of AH36 during laser and CWW GMAW arc hybrid welding
In order to analyze the influence of the distance between heat sources (DLA) on the welding process, the effects of DLA on the droplet transfer behavior, weld formation characteristics and weld formation mechanis...
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Article
[Rb3BaCl][In8Se14]: Compressed chalcopyrite-type selenide achieved by polycationic substitution strategy toward excellent nonlinear optical property
Incorporation of monovalent Ag+ or Li+ ions into the anionic groups MQ22− (M = Ga, In; Q = S, Se) within diamond-like structures holds great promise for the second-order nonlinear optical (NLO) crystals. However,...
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Article
Entrained Defects in A356 Semisolid Slurry Produced by RSF and CSC Processes
Semisolid slurry is highly important in rheocasting. In the majority of semisolid slurry preparation methods, the melt is subjected to intensive stirring. In the present study, experiments, simulations, SEM, X...
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Brigatinib, a newly discovered AXL inhibitor, suppresses AXL-mediated acquired resistance to osimertinib in EGFR-mutated non-small cell lung cancer
In addition to the classical resistance mechanisms, receptor tyrosine-protein kinase AXL is a main mechanism of resistance to third-generation epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-T...
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Oral mitochondrial transplantation using nanomotors to treat ischaemic heart disease
Mitochondrial transplantation is an important therapeutic strategy for restoring energy supply in patients with ischaemic heart disease (IHD); however, it is limited by the invasiveness of the transplantation ...
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Holographic images of an AdS black hole within the framework of f(R) gravity theory
Based on the AdS/CFT correspondence, this study employs an oscillating Gaussian source to numerically study the holographic images of an AdS black hole under f(R) gravity using wave optics. Due to the diffraction...
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Open AccessConformal thyroidectomy is a feasible option in papillary thyroid microcarcinoma: a retrospective cohort study with 10-year follow-up results
In recent years, there has been an increasing prevalence of patients with papillary thyroid microcarcinoma (PTMC) without lymph node involvement in medical centers worldwide. For patients who are unable to und...