110 Result(s)

Article

Conformal thyroidectomy is a feasible option in papillary thyroid microcarcinoma: a retrospective cohort study with 10-year follow-up results

In recent years, there has been an increasing prevalence of patients with papillary thyroid microcarcinoma (PTMC) without lymph node involvement in medical centers worldwide. For patients who are unable to und...

Chen Li, Jian Cao, Guo-Shuai Chen, **ao-Dong Yang… in Langenbeck's Archives of Surgery (2024)

Article

50% efficacy dose of intravenous lidocaine in supressing sufentanil-induced cough in children: a randomised controlled trial

Opioids such as sufentanil are used as anaesthetics due to their rapid action and superior analgesic effect. However, sufentanil induces a huge cough in paediatric patients. In contrast, intravenous (IV) lidoc...

Yang Hu, Ming-cheng Du, Guo-hong Zhu, **ang Long, **g-**g Jiang… in BMC Anesthesiology (2024)

Article

Extracellular matrix protein 1 (ECM1) is a potential biomarker in B cell acute lymphoblastic leukemia

B cell acute lymphoblastic leukemia (ALL) is characterized by the highly heterogeneity of pathogenic genetic background, and there are still approximately 30–40% of patients without clear molecular markers. To...

Li-**n Wu, Ming-Yue Zhao, Nan Yan, Ya-Lan Zhou… in Clinical and Experimental Medicine (2024)

Article

TBK1, a prioritized drug repurposing target for amyotrophic lateral sclerosis: evidence from druggable genome Mendelian randomization and pharmacological verification in vitro

There is a lack of effective therapeutic strategies for amyotrophic lateral sclerosis (ALS); therefore, drug repurposing might provide a rapid approach to meet the urgent need for treatment.

Qing-Qing Duan, Han Wang, Wei-Ming Su, **ao-**g Gu, **ao-Fei Shen… in BMC Medicine (2024)

Article

Proteomic profiling of cerebrospinal fluid in pediatric myelin oligodendrocyte glycoprotein antibody-associated disease

Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD) is an autoimmune demyelinating disorder of the central nervous system.

Yi-Long Wang, Meng-Ying Zhu, Zhe-Feng Yuan, **ao-Yan Ren… in World Journal of Pediatrics (2024)

Article

Can single progesterone concentration predict miscarriage in early pregnant women with threatened miscarriage: a systematic review and meta-analysis

About 25% of pregnant women experience bleeding in the early stage, and half of them eventually progress to pregnancy loss. Progesterone serves as a useful biomarker to predict miscarriage in threatened miscar...

Yi Gong, Tong Jiang, Yang Sun, Guo-Lin Wu, Bu-Wei Han… in BMC Pregnancy and Childbirth (2024)

Article

Monitoring of urinary iodine concentration in naval pilots: should iodine be supplemented or limited at coastal stations?

Jia Zeng, Qi Li, **ang Lu, Dan-Dan Liu, Rong-Guan Jiao… in Military Medical Research (2024)

Article

A nitrous oxide/oxygen fixed mixture to reduce pain induced by the hypodermic injection: study protocol for a randomized, controlled trial

Patients with hematological malignancies received multiple hypodermic injections of recombinant human granulocyte colony-stimulating factor. Procedural pain is one of the most common iatrogenic causes of pain ...

Jun-Jun Zhang, ** Yu, Hui Dang, Cheng-Shuang Feng, **u-Jiang Long, Wen-Fa Huang… in Trials (2024)

Article

Inhibition of STAT3 alleviates LPS-induced apoptosis and inflammation in renal tubular epithelial cells by transcriptionally down-regulating TASL

Systemic lupus erythematosus (SLE) is a common autoimmune disease that impacts various organs. Lupus nephritis (LN) significantly contributes to death in children with SLE. Toll-like receptor (TLR) adaptor int...

**-Wen Xu, Ming-Yan Wang, Yan Mao, Zheng-Yun Hu… in European Journal of Medical Research (2024)

Article

Erratum to: ARID1A Inactivation Increases Expression of circ0008399 and Promotes Cisplatin Resistance in Bladder Cancer

Yang-kai Jiang, Yu-jun Shuai, Hua-min Ding, Hui Zhang… in Current Medical Science (2023)

Article

Metatranscriptome of human lung microbial communities in a cohort of mechanically ventilated COVID-19 Omicron patients

The Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) infected a substantial proportion of Chinese population, and understanding the factors underlying the severity of the dis...

Lin Wang, Jia-Bao Cao, Bin-Bin **a, Yue-Juan Li… in Signal Transduction and Targeted Therapy (2023)

Article

Uncovering neural pathways underlying bulimia nervosa: resting-state neural connectivity disruptions correlate with maladaptive eating behaviors

Bulimia nervosa (BN) is characterized by recurrent binge-eating episodes and inappropriate compensatory behaviors. This study investigated alterations in resting-state surface-based neural activity in BN patie...

Jia-ni Wang, Miao Wang, Guo-wei Wu… in Eating and Weight Disorders - Studies on A… (2023)

Article

Metformin accelerates bone fracture healing by promoting type H vessel formation through inhibition of YAP1/TAZ expression

Due to increasing morbidity worldwide, fractures are becoming an emerging public health concern. This study aimed to investigate the effect of metformin on the healing of osteoporotic as well as normal fractur...

Zhe Ruan, Hao Yin, Teng-Fei Wan, Zhi-Rou Lin, Shu-Shan Zhao, Hai-Tao Long… in Bone Research (2023)

Article

Reconsidering N component of cancer staging for T1-2N0-2M0 small-cell lung cancer: a retrospective study based on multicenter cohort

The current nodal (pN) classification still has limitations in stratifying the prognosis of small cell lung cancer (SCLC) patients with pathological classifications T1-2N0-2M0. Thus. This study aimed to develo...

Lei-Lei Wu, Li-Hong Qiu, **aolu Chen, Wan-Jun Yu, Chong-Wu Li… in Respiratory Research (2023)

Article

AMG-510 and cisplatin combination increases antitumor effect in lung adenocarcinoma with mutation of KRAS G12C: a preclinical and translational research

The efficacy of monotherapy of AMG-510 is limited. This study explored whether the AMG-510 and cisplatin combination increases the anti-tumor effect in lung adenocarcinoma with the mutation of Kirsten rat sarc...

Lei-Lei Wu, Wen-Mei Jiang, Zhi-Yuan Liu, Yi-Yi Zhang, Jia-Yi Qian… in Discover Oncology (2023)

Article

Discrimination of Baphicacanthis Cusiae Rhizoma et radix and its adulterant species and establishment of an assay method for quality control

Baphicacanthis Cusiae Rhizoma et Radix, commonly known as Nan-Ban-Lan-Gen (NBLG), is an essential traditional Chinese medicine that possesses diverse bioactivities, particularly noteworthy for its antiviral prope...

Yue Li, Qiong-** Yu, Lee-Fong Yau, Guo-Kai Huang, **g-Guang Lu… in Chinese Medicine (2023)

Article

Comparing the effectiveness and safety of Sorafenib plus TACE with Apatinib plus TACE for treating patients with unresectable hepatocellular carcinoma: a multicentre propensity score matching study

Local combined systemic therapy has been an important method for the treatment of unresectable hepatocellular carcinoma (HCC).The purpose of this study was to compare the effectiveness and safety of transarter...

Liang Yin, Kai-Cai Liu, Wei-Fu Lv, Dong Lu, Yu-Lin Tan, Guo-**ang Wang… in Cancer Imaging (2023)

Article

Biomimetic natural biomaterials for tissue engineering and regenerative medicine: new biosynthesis methods, recent advances, and emerging applications

Biomimetic materials have emerged as attractive and competitive alternatives for tissue engineering (TE) and regenerative medicine. In contrast to conventional biomaterials or synthetic materials, biomimetic s...

Shuai Liu, Jiang-Ming Yu, Yan-Chang Gan, **ao-Zhong Qiu… in Military Medical Research (2023)

Article

Blockade of NMT1 enzymatic activity inhibits N-myristoylation of VILIP3 protein and suppresses liver cancer progression

Hepatocellular carcinoma (HCC) is one of the most common malignant tumors. Identification of the underlying mechanism of HCC progression and exploration of new therapeutic drugs are urgently needed. Here, a co...

**ang-Peng Tan, Yan He, **g Yang, **an Wei… in Signal Transduction and Targeted Therapy (2023)

Article

The development of a cSMART-based integrated model for hepatocellular carcinoma diagnosis

Hepatocellular carcinoma (HCC) generally arises from a background of liver cirrhosis (LC). Patients with cirrhosis and suspected HCC are recommended to undergo serum biomarker tests and imaging diagnostic eval...

Tong Wu, Rong Fan, Jian Bai, Zhao Yang, Yun-Song Qian… in Journal of Hematology & Oncology (2023)