-
Article
Open AccessLife time suicidal thoughts in an urban community in Hanoi, Vietnam
Suicidal thought is a risk factor and a stage in the suicidal process from planning to attempting and dying by suicide. To date, studies on suicidal thought in the general population, especially in Asian commu...
-
Article
Reduced Anxiety and Depression-Like Behaviors in Mice Lacking GABA Transporter Subtype 1
γ-Aminobutyric acid (GABA) transporter subtype 1 (GAT1), which transports extracellular GABA into presynaptic neurons, plays an important regulatory role in the function of GABAergic systems. However, the contr.....
-
Article
Open AccessHIV/STD pattern and its associated risk factors among male STD clinic attendees in China: a foci for HIV intervention
Previous studies suggested a high prevalence of STDs including HIV among female sex workers and men who have sex with men in China, but little was known about the prevalence in male patients attending public S...
-
Article
Open AccessRisk factors for Mycoplasma genitalium infection among female sex workers: a cross-sectional study in two cities in southwest China
Mycoplasma genitalium (MG) is one of the common causes of non-gonococcal urethritis (NGU) in men and is associated with cervicitis, endometritis, and pelvic inflammatory diseases (PID) in women. The prevalence o...
-
Article
Open AccessThe prevalences of Neisseria gonorrhoeae and Chlamydia trachomatis infections among female sex workers in China
Sexually transmitted infections (STIs) have become a major public health problem among female sex workers (FSWs) in China. There have been many studies on prevalences of HIV and syphilis but the data about Neisse...
-
Article
Open AccessThe prevalence of urethral and rectal Mycoplasma genitalium among men who have sex with men in China, a cross-sectional study
Although Mycoplasma genitalium (MG) is a common sexually transmitted infection (STI), very little information regarding the prevalence of MG among MSM (men who have sex with men) is available in China. The object...
-
Article
Open AccessBiClamp® forcep liver transection versus clamp crushing technique for liver resection: study protocol for a randomized controlled trial
Blood loss and the requirement of blood transfusions during liver transection have been shown to correlate well with higher morbidity and mortality rates and a worse prognosis. Various devices for liver parenc...
-
Article
Sheehan’s syndrome in **njiang: Clinical characteristics and laboratory evaluation of 97 patients
OBJECTIVE: To evaluate the clinical and hormonal characteristics of patients with Sheehan’s syndrome in **njiang, China. METHODS: 97 cases diagnosed as Sheehan’s syndrome in our hospital from 1999 to 2013 were...
-
Article
Open AccessOne-layer versus two-layer duct-to-mucosa pancreaticojejunostomy after pancreaticoduodenectomy: study protocol for a randomized controlled trial
Although various pancreaticojejunal duct-to-mucosa anastomosis methods have been developed to reduce the postoperative risks of pancreaticoduodenectomy, pancreatic fistula remains the most serious complication...
-
Article
Open AccessA fixed inhaled nitrous oxide/oxygen mixture as an analgesic for adult cancer patients with breakthrough pain: study protocol for a randomized controlled trial
The management of breakthrough pain in cancer patients is always a challenge for medical professions. Occurring in 80% of cancer patients with advanced disease, breakthrough pain significantly decreases both p...
-
Article
Open AccessCharacteristics of exercise capacity in female systemic lupus erythematosus associated pulmonary arterial hypertension patients
To study the oxygen uptake efficiency and determine usefulness of submaximal parameters of oxygen uptake in systemic lupus erythematosus associated pulmonary arterial hypertension (SLE PAH) on performing a car...
-
Article
Open AccessComprehensive functional annotation of susceptibility SNPs prioritized 10 genes for schizophrenia
Nearly 95% of susceptibility SNPs identified by genome-wide association studies (GWASs) are located in non-coding regions, which causes a lot of difficulty in deciphering their biological functions on disease ...
-
Article
Open AccessCorrection: Epalrestat, an Aldose Reductase Inhibitor, Restores Erectile Function in Streptozocin-induced Diabetic Rats
This Article was originally published under Nature Research’s License to Publish, but has now been made available under a CC BY 4.0 license. The PDF and HTML versions of the Article have been modified accordin...
-
Article
Open AccessEpalrestat, an Aldose Reductase Inhibitor, Restores Erectile Function in Streptozocin-induced Diabetic Rats
Epalrestat, an aldose reductase inhibitor (ARI), was adopted to improve the function of peripheral nerves in diabetic patients. The aim of this study was to investigate whether epalrestat could restore the ere...
-
Article
Open AccessRole of the PPAR pathway in atrial fibrillation associated with heart valve disease: transcriptomics and proteomics in human atrial tissue
-
Article
Open AccessImproving the accuracy and efficacy of diagnosing polycystic ovary syndrome by integrating metabolomics with clinical characteristics: study protocol for a randomized controlled trial
Polycystic ovary syndrome (PCOS) is a complex endocrine syndrome with poorly understood mechanisms. To provide patients with PCOS with individualized therapy, it is critical to precisely diagnose the phenotype...
-
Article
Open AccessFactors associated with public attitudes towards persons with disabilities: a systematic review
The aim of this review is to identify and summarize factors that are associated with public attitudes towards people with various disabilities systematically.
-
Article
Open AccessCD147 receptor is essential for TFF3-mediated signaling regulating colorectal cancer progression
Major gaps in understanding the molecular mechanisms of colorectal cancer (CRC) progression and intestinal mucosal repair have hampered therapeutic development for gastrointestinal disorders. Trefoil factor 3 ...
-
Article
Open AccessA novel missense variant in ACAA1 contributes to early-onset Alzheimer’s disease, impairs lysosomal function, and facilitates amyloid-β pathology and cognitive decline
Alzheimer’s disease (AD) is characterized by progressive synaptic dysfunction, neuronal death, and brain atrophy, with amyloid-β (Aβ) plaque deposits and hyperphosphorylated tau neurofibrillary tangle accumula...
-
Article
Open AccessDetection of an anti-angina therapeutic module in the effective population treated by a multi-target drug Danhong injection: a randomized trial
It’s a challenge for detecting the therapeutic targets of a polypharmacological drug from variations in the responsed networks in the differentiated populations with complex diseases, as stable coronary heart ...