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  1. Article

    Open Access

    BiClamp® forcep liver transection versus clamp crushing technique for liver resection: study protocol for a randomized controlled trial

    Blood loss and the requirement of blood transfusions during liver transection have been shown to correlate well with higher morbidity and mortality rates and a worse prognosis. Various devices for liver parenc...

    Jiang-ming Chen, Wei Geng, Fu-bao Liu, Hong-chuan Zhao, Sheng-xue **e, Hui Hou in Trials (2015)

  2. Article

    Open Access

    One-layer versus two-layer duct-to-mucosa pancreaticojejunostomy after pancreaticoduodenectomy: study protocol for a randomized controlled trial

    Although various pancreaticojejunal duct-to-mucosa anastomosis methods have been developed to reduce the postoperative risks of pancreaticoduodenectomy, pancreatic fistula remains the most serious complication...

    Shu-bo Pan, Wei Geng, Da-chen Zhou, Jiang-ming Chen, Hong-chuan Zhao, Fu-bao Liu in Trials (2016)

  3. Article

    Open Access

    A fixed inhaled nitrous oxide/oxygen mixture as an analgesic for adult cancer patients with breakthrough pain: study protocol for a randomized controlled trial

    The management of breakthrough pain in cancer patients is always a challenge for medical professions. Occurring in 80% of cancer patients with advanced disease, breakthrough pain significantly decreases both p...

    Qiang Liu, Yu Wang, **ang-Jiang Luo, Ning-Ju Wang, ** Chen, **n **, Guo-**a Mu in Trials (2017)

  4. Article

    Open Access

    Improving the accuracy and efficacy of diagnosing polycystic ovary syndrome by integrating metabolomics with clinical characteristics: study protocol for a randomized controlled trial

    Polycystic ovary syndrome (PCOS) is a complex endocrine syndrome with poorly understood mechanisms. To provide patients with PCOS with individualized therapy, it is critical to precisely diagnose the phenotype...

    Cheng-Ming Ni, Wen-Long Huang, Yan-Min Jiang, Juan Xu, Ru Duan, Yun-Long Zhu in Trials (2020)

  5. Article

    Open Access

    Both indirect maternal and direct fetal genetic effects reflect the observational relationship between higher birth weight and lower adult bone mass

    Birth weight is considered not only to undermine future growth, but also to induce lifelong diseases; the aim of this study is to explore the relationship between birth weight and adult bone mass.

    Jiang-Wei **a, Lin Zhang, ** Li, Cheng-Da Yuan, **ao-Wei Zhu, Yu Qian in BMC Medicine (2022)

  6. Article

    Open Access

    Inhibition of STAT3 alleviates LPS-induced apoptosis and inflammation in renal tubular epithelial cells by transcriptionally down-regulating TASL

    Systemic lupus erythematosus (SLE) is a common autoimmune disease that impacts various organs. Lupus nephritis (LN) significantly contributes to death in children with SLE. Toll-like receptor (TLR) adaptor int...

    **-Wen Xu, Ming-Yan Wang, Yan Mao, Zheng-Yun Hu in European Journal of Medical Research (2024)

  7. Article

    Open Access

    A nitrous oxide/oxygen fixed mixture to reduce pain induced by the hypodermic injection: study protocol for a randomized, controlled trial

    Patients with hematological malignancies received multiple hypodermic injections of recombinant human granulocyte colony-stimulating factor. Procedural pain is one of the most common iatrogenic causes of pain ...

    Jun-Jun Zhang, ** Yu, Hui Dang, Cheng-Shuang Feng, **u-Jiang Long, Wen-Fa Huang in Trials (2024)

  8. Article

    Open Access

    TBK1, a prioritized drug repurposing target for amyotrophic lateral sclerosis: evidence from druggable genome Mendelian randomization and pharmacological verification in vitro

    There is a lack of effective therapeutic strategies for amyotrophic lateral sclerosis (ALS); therefore, drug repurposing might provide a rapid approach to meet the urgent need for treatment.

    Qing-Qing Duan, Han Wang, Wei-Ming Su, **ao-**g Gu, **ao-Fei Shen in BMC Medicine (2024)