11 Result(s)

Article

De novo design of a nanoregulator for the dynamic restoration of ovarian tissue in cryopreservation and transplantation

The cryopreservation and transplantation of ovarian tissue underscore its paramount importance in safeguarding reproductive capacity and ameliorating reproductive disorders. However, challenges persist in ovar...

Min Jiang, Guo-Hui Zhang, Yuan Yu, Yu-Hong Zhao, Jun Liu… in Journal of Nanobiotechnology (2024)

Article

Tumor-targeting hydroxyapatite nanoparticles for remodeling tumor immune microenvironment (TIME) by activating mitoDNA-pyroptosis pathway in cancer

In recent years, immunotherapy has emerged as a promising strategy for treating solid tumors, although its efficacy remains limited to a subset of patients. Transforming non-responsive “cold” tumor types into ...

Yuxuan Yang, Jia Yang, Nan Zhu, Haosen Qiu, Wenxiang Feng… in Journal of Nanobiotechnology (2023)

Article

Enzymatic Characterization and Coenzyme Specificity Conversion of a Novel Dimeric Malate Dehydrogenase from Bacillus subtilis

Malate is an important material to various industrials and clinical applications. Bacillus subtilis is a widely used biocatalyst tool for chemical production. However, the specific enzymatic properties of malate ...

Ya-Dong Ge, Yi-Tian Guo, Lu-Lu Jiang, Hui-Hui Wang, Shao-Lin Hou… in The Protein Journal (2023)

Article

Targeted delivery of fat extract by platelet membrane-cloaked nanocarriers for the treatment of ischemic stroke

Our previous studies suggest that human fat extract (FE) contains a variety of angiogenic factors and may provide an alternative treatment option for stroke. However, the therapeutic effect is largely limited ...

Cheng Wang, Xuewei Yang, Yixu Jiang, Lin Qi, Deli Zhuge… in Journal of Nanobiotechnology (2022)

Article

Chromosome engineering of Escherichia coli for constitutive production of salvianic acid A

Salvianic acid A (SAA), a valuable natural product from herbal plant Salvia miltiorrhiza, exhibits excellent antioxidant activities on food industries and efficacious therapeutic potential on cardiovascular disea...

Liang Zhou, Qi Ding, Guo-Zhen Jiang, Zhen-Ning Liu… in Microbial Cell Factories (2017)

Article

Enhanced production of polyhydroxybutyrate by multiple dividing E. coli

Most bacteria are grown in a binary fission way meaning a bacterial cell is equally divided into two. Polyhydroxyalkanoates (PHA) can be accumulated as inclusion bodies by bacteria. The cell division way and m...

Hong Wu, Zhongyun Fan, **aoran Jiang, **chun Chen… in Microbial Cell Factories (2016)

Article

Metabolic flux responses to genetic modification for shikimic acid production by Bacillus subtilis strains

Shikimic acid (SA) is a key chiral starting molecule for the synthesis of the neuramidase inhibitor GS4104 against viral influenza. Microbial production of SA has been extensively investigated in Escherichia coli

Dong-Feng Liu, Guo-Min Ai, Qing-**ang Zheng, Chang Liu… in Microbial Cell Factories (2014)

Article

Hyperproduction of poly(4-hydroxybutyrate) from glucose by recombinant Escherichia coli

Poly(4-hydroxybutyrate) [poly(4HB)] is a strong thermoplastic biomaterial with remarkable mechanical properties, biocompatibility and biodegradability. However, it is generally synthesized when 4-hydroxybutyra...

**ao-Yun Zhou, **ao-** Yuan, Zhen-Yu Shi, De-Chuang Meng… in Microbial Cell Factories (2012)

Article

Identification and characterization of a novel fumarase gene by metagenome expression cloning from marine microorganisms

Fumarase catalyzes the reversible hydration of fumarate to L-malate and is a key enzyme in the tricarboxylic acid (TCA) cycle and in amino acid metabolism. Fumarase is also used for the industrial production of L

Chengjian Jiang, Lan-Lan Wu, Gao-Chao Zhao, Pei-Hong Shen… in Microbial Cell Factories (2010)

Article

Erratum to: Bacterially Expressed Double-Stranded RNAs against Hot-Spot Sequences of Tobacco Mosaic Virus or Potato Virus Y Genome Have Different Ability to Protect Tobacco from Viral Infection

Guo-Hua Yin, Zhao-Nan Sun, Yun-Zhi Song… in Applied Biochemistry and Biotechnology (2010)

Article

Assembly, Morphology and Thermal Stability of Polyamide 6 Nanotubes

Polyamide 6 (PA6) nanotubes array has been prepared successfully using small pore anodic aluminum oxide (AAO) membrane (200 nm) as the template via polymer solution and melt wetting method. The investigation of S...

Jian-Jiang Li, Guo-Jun Song, **-Lin She, ** Han, Zhi Peng, Dong Chen in Polymer Journal (2006)