6 Result(s)
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Article
Guillaume Marçais
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Article
Open AccessLarge scale sequence alignment via efficient inference in generative models
Finding alignments between millions of reads and genome sequences is crucial in computational biology. Since the standard alignment algorithm has a large computational cost, heuristics have been developed to s...
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Open AccessHarvestman: a framework for hierarchical feature learning and selection from whole genome sequencing data
Supervised learning from high-throughput sequencing data presents many challenges. For one, the curse of dimensionality often leads to overfitting as well as issues with scalability. This can bring about inacc...
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Open AccessA new rhesus macaque assembly and annotation for next-generation sequencing analyses
The rhesus macaque (Macaca mulatta) is a key species for advancing biomedical research. Like all draft mammalian genomes, the draft rhesus assembly (rheMac2) has gaps, sequencing errors and misassemblies that hav...
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Open AccessDecoding the massive genome of loblolly pine using haploid DNA and novel assembly strategies
The size and complexity of conifer genomes has, until now, prevented full genome sequencing and assembly. The large research community and economic importance of loblolly pine, Pinus taeda L., made it an early ca...
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Open AccessParsimonious reconstruction of network evolution
Understanding the evolution of biological networks can provide insight into how their modular structure arises and how they are affected by environmental changes. One approach to studying the evolution of thes...
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Open AccessA whole-genome assembly of the domestic cow, Bos taurus
The genome of the domestic cow, Bos taurus, was sequenced using a mixture of hierarchical and whole-genome shotgun sequencing methods.
