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Management of atrial fibrillation: two decades of progress — a scientific statement from the European Cardiac Arrhythmia Society
Atrial fibrillation (AF) is the most common sustained arrhythmia encountered in clinical practice. The aim of this review was to evaluate the progress made in the management of AF over the two last decades.
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Article
Clinical classification and the subclinical atrial fibrillation challenge: a position paper of the European Cardiac Arrhythmia Society
Symptomatic atrial fibrillation (AF) or clinical AF is associated with impaired quality of life, higher risk of stroke, heart failure, and increased mortality. Current clinical classification of AF is based on...
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Authors’ reply concerning the letter by Ensminger et al.
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Open AccessUse of vitamin K antagonists for secondary stroke prevention depends on the treating healthcare provider in Germany – results from the German AFNET registry
Anticoagulation using vitamin K antagonists (VKAs) significantly reduces the risk of recurrent stroke in stroke patients with atrial fibrillation (AF) and is recommended by guidelines.
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Balloon valvuloplasty for treatment of cardiogenic shock in the era of surgical valve replacement and TAVI
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Open AccessSPECT myocardial perfusion imaging as an adjunct to coronary calcium score for the detection of hemodynamically significant coronary artery stenosis
Coronary artery calcifications (CAC) are markers of coronary atherosclerosis, but do not correlate well with stenosis severity. This study intended to evaluate clinical situations where a combined approach of ...
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Article
Transcatheter Edwards Sapien XT valve in valve implantation in degenerated aortic bioprostheses via transfemoral access
Surgical treatment of degenerated aortic bioprostheses is associated with an increased risk of morbidity and mortality, especially in elderly patients with significant co-morbidities. Therefore, transcatheter ...
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Article
Meta-analysis identifies six new susceptibility loci for atrial fibrillation
Patrick Ellinor and colleagues report a meta-analysis of genome-wide association studies for atrial fibrillation in European populations. They identify six newly associated loci, four of which were replicated ...
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Common variants in KCNN3 are associated with lone atrial fibrillation
Patrick Ellinor and colleagues report a genome-wide association study identifying variants in KCNN3 associated to lone atrial fibrillation.
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Open AccessMMP-1 serum levels predict coronary atherosclerosis in humans
Myocardial infarction results as a consequence of atherosclerotic plaque rupture, with plaque stability largely depending on the lesion forming extracellular matrix components. Lipid enriched non-calcified les...
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Open AccessAcute stent thrombosis in a sirolimus eluting stent after wasp sting causing acute myocardial infarction: a case report
Hymenoptera venoms contain thrombogenic substances that might be responsible for cardiovascular events independent of anaphylactic reactions.
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Article
Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry
Emelia Benjamin and colleagues report a meta-analysis of genome-wide association study data for atrial fibrillation, a condition associated with stroke and heart failure, in five European community-based cohor...
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Article
Current state of knowledge and experts’ perspective on the subcutaneous implantable cardioverter-defibrillator
ICD implantation is today a well-recognized therapy to prevent sudden cardiac death. The available implantable devices at present need the use of permanent endocavitary leads which may cause, in some instances...
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Article
Common variants at ten loci modulate the QT interval duration in the QTSCD Study
Arne Pfeufer, Aravinda Chakravarti and colleagues from the QTSCD consortium report genetic associations influencing the QT interval duration, a measure of cardiac repolarization which is a risk factor for sudd...
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Detection of significant coronary artery stenosis with 64-slice computed tomography in heart transplant recipients: a comparative study with conventional coronary angiography
Purpose The present study evaluates clinical feasibility of cardiac multidetector computed tomography angiography (MDCTA) to detect significant stenosis of coronary vessels due to transpl...
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The German Competence Network on Atrial Fibrillation (AFNET)
The German Competence Network on Atrial Fibrillation (AFNET) is an interdisciplinary national research network funded by the Federal Ministry of Education and Research (BMBF) since 2003. The AFNET aims at impr...
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Open AccessPredictive value of coronary calcifications for future cardiac events in asymptomatic patients with diabetes mellitus: A prospective study in 716 patients over 8 years
To establish an efficient prophylaxis of coronary artery disease reliable risk stratification is crucial, especially in the high risk population of patients suffering from diabetes mellitus. This prospective s...
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Characteristics of coronary plaques before angiographic progression determined by Multi-Slice CT
The aim of the present study was to characterize coronary plaques by Multi-Slice Computed Tomography (Siemens sensation 16, Forcheim, Germany) before significant angiographic progression occurred and to compar...
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Article
Cardiac sarcoidosis concealed by arrhythmogenic right ventricular dysplasia/cardiomyopathy
A definitive diagnosis of cardiac sarcoidosis relies on the results of endomyocardial biopsy. In this Case Study Greif et al. describe a patient whose biopsy was negative for sarcoidosis—leading to a diagnosis of...
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Article
Torsades de Pointes: A Rare Complication of an Extra-Adrenal Pheochromocytoma
Pheochromocytoma is an infrequent secondary cause of arterial hypertension, often associated with paroxysmal headache, sweating, weight loss, and palpitations. Cardiovascular complications of pheochromocytoma ...