13 Result(s)
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Article
Gao **ang
Biomedicine
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Article
Open AccessTh1 cells contribute to retinal ganglion cell loss in glaucoma in a VCAM-1-dependent manner
Glaucoma is a complex neurodegenerative disorder characterized by the progressive loss of retinal ganglion cells (RGC) and optic nerve axons, leading to irreversible visual impairment. Despite its clinical sig...
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Open AccessCausal associations between gut microbiota and urological tumors: a two-sample mendelian randomization study
Dysbiosis of gut microbiota has been linked to numerous diseases, including cancer. The unique role of gut microbiota in urological tumors is gaining prominence. However, it is still controversial whether the ...
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Open AccessClinical significance and potential regulatory mechanism of overexpression of pituitary tumor-transforming gene transcription factor in bladder cancer
Pituitary tumor transforming gene-1 (PTTG1) transcription factor is identified as carcinogenic and associated with tumor invasiveness, but its role in bladder cancer (BLCA) remains obscure. This research is in...
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Publisher Correction: Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma
In the version of this article originally published, there was an error in the URL linked to by an accession code in the data availability section of the methods. The erroneous URL was: https:/...
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Open AccessEvaluation of efficacy and safety for Brucea javanica oil emulsion in the control of the malignant pleural effusions via thoracic perfusion
Brucea javanica oil emulsion (BJOE) is traditional Chinese medicine with implicated anti-tumor activity, which has been used for treating lung cancer in China. The aim of this investigation was to evaluate the...
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Open AccessDownregulating ANP32A rescues synapse and memory loss via chromatin remodeling in Alzheimer model
The impairment of histone acetylation is causally linked to the cognitive decline in Alzheimer’s disease (AD). In addition to histone acetyltransferases (HATs) and histone deacetylases (HDACs), inhibitor of ac...
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Correction: Corrigendum: The genome sequence of the orchid Phalaenopsis equestris
Nat. Genet. 47, 65–72 (2015); published online 24 November 2014; corrected after print 9 January 2015; corrected after print 6 February 2015 In the version of this article initially published, the legend for F...
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Correction: Corrigendum: The genome sequence of the orchid Phalaenopsis equestris
Nat. Genet. 47, 65–72 (2015); published online 24 November 2014; corrected after print 9 January 2015 In the version of this article initially published, the divergence time estimates in Figure 1b were incorre...
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Open AccessThe genome sequence of the orchid Phalaenopsis equestris
Zhong-Jian Liu, Lai-Qiang Huang, Yi-Bo Luo, Hong-Hwa Chen and Yves Van de Peer report the first genome sequence of a crassulacean acid metabolism (CAM) plant, the orchid Phalaenopsis equestris. They identify gene...
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Evaluation of doxorubicin-loaded pH-sensitive polymeric micelle release from tumor blood vessels and anticancer efficacy using a dorsal skin-fold window chamber model
To evaluation the doxorubicin (DOX)-loaded pH-sensitive polymeric micelle release from tumor blood vessels into tumor interstitium using an animal vessel visibility model, the so-called dorsal skin-fold window...
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Co-activation of nAChR and mGluR induces γ oscillation in rat medial septum diagonal band of Broca slices
To examine whether co-activation of nAChR and mGluR1 induced γ oscillation (20–60 Hz) in rat medial septum diagonal band of Broca (MSDB) slices.
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Open AccessApoptosis of Human Pancreatic Carcinoma PC-2 Cells by an Antisense Oligonucleotide Specific to Point Mutated K-ras
The prognosis of pancreatic carcinoma is poor due to the difficulty in early diagnosis, insensitivity to routine therapies and limited understanding of its pathological mechanisms. Gene therapy is now becoming...
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Effects of nicotine stimulation on spikes, theta frequency oscillations, and spike-theta oscillation relationship in rat medial septum diagonal band Broca slices
Spiking activities and neuronal network oscillations in the theta frequency range have been found in many cortical areas during information processing. The aim of this study is to determine whether nicotinic a...
